{"id":"W4388231839","doi":"10.51731/cjht.2023.774","title":"Tisagenlecleucel (Kymriah)","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Reimbursement; Medicine; Refractory (planetary science); Food and drug administration; Drug; Intensive care medicine; Medical emergency; Pharmacology; Political science; Health care","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004630827,0.0004267665,0.0003648355,0.0009656188,0.0004256344,0.0009840417,0.0005521125,0.0009908029,0.08534621],"category_scores_gemma":[0.0006122584,0.0001152741,0.0004140867,0.0006092367,0.0004292459,0.0005466494,0.0005492991,0.001004114,0.02412612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001701258,"about_ca_system_score_gemma":0.003055506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02173153,"about_ca_topic_score_gemma":0.06174289,"domain_scores_codex":[0.9996672,0.00003955877,0.00002086514,0.00004726751,0.0001713968,0.00005379331],"domain_scores_gemma":[0.9996693,0.00004277006,0.00005015361,0.00001384376,0.0001311164,0.00009278419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005218528,0.0001099662,0.0004958573,0.002366894,0.00005314283,0.0002648582,0.00005427612,0.0001880387,0.01084945,0.006266488,0.2968401,0.681989],"study_design_scores_gemma":[0.0001348192,0.000326807,0.0009821949,0.0003472467,0.00002399657,0.0003336157,0.00002322596,0.00007929157,0.003034684,0.000272085,0.9944332,0.000008810351],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.01406724,0.3382377,0.003280574,0.01041605,0.004746808,0.0006487046,0.008615538,0.001759708,0.6182277],"genre_scores_gemma":[0.1185085,0.168533,0.006142973,0.01369215,0.0009957114,0.0003939352,0.01417753,0.000288974,0.6772672],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.08534621,"threshold_uncertainty_score":0.2855116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07828658743759795,"score_gpt":0.3642542119651817,"score_spread":0.2859676245275837,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}