{"id":"W4388268054","doi":"10.1016/j.jcjd.2023.10.255","title":"OSILODROSTAT DOSING CONSIDERATIONS IN CUSHING'S DISEASE: A POOLED ANALYSIS OF 229 INDIVIDUALS ACROSS LINC 2, LINC 3, AND LINC 4","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Pituitary Gland Disorders and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Medicine; Dosing; Pooled analysis; Internal medicine; Meta-analysis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002138778,0.0004860965,0.001588786,0.0007697949,0.0004221488,0.0007612917,0.0004108145,0.0004481165,0.001102377],"category_scores_gemma":[0.003530529,0.0004314964,0.004007708,0.001559061,0.0002486695,0.0003561728,0.0005464226,0.0003627759,0.000131478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006657724,"about_ca_system_score_gemma":0.0005976657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01681087,"about_ca_topic_score_gemma":0.03303567,"domain_scores_codex":[0.9974045,0.0009575853,0.0004435056,0.000610029,0.0003705824,0.0002137279],"domain_scores_gemma":[0.9981136,0.0006102657,0.0006085866,0.0003276613,0.0002535467,0.00008625044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.02128816,0.0001821539,0.8880649,0.0007899587,0.06030442,0.00036314,0.0002797568,0.0006023816,0.00279056,0.0001394901,0.0009795482,0.02421546],"study_design_scores_gemma":[0.0007777245,0.001265895,0.9552114,0.00008851928,0.03932073,0.0002499244,0.0003148806,0.0006588597,0.0004046538,0.00009520735,0.001568183,0.0000440044],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873495,0.008583566,0.001114936,0.00005074582,0.00004593195,0.00006668505,0.00202195,0.00002538355,0.0007413468],"genre_scores_gemma":[0.9973872,0.0006431345,0.0003901978,0.0000575839,0.00001905735,0.00003398069,0.001217535,0.000008565257,0.0002427776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01681087,"threshold_uncertainty_score":0.03342605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01800776096049337,"score_gpt":0.2843733048915473,"score_spread":0.2663655439310539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}