{"id":"W4388270454","doi":"10.1016/j.jcjd.2023.10.334","title":"MULTIPARAMETRIC RESPONSE TO DISEASE-MODIFYING THERAPY FOR TRANSTHYRETIN AMYLOIDOSIS CARDIOMYOPATHY","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Calgary Laboratory Services","funders":"","keywords":"Medicine; Transthyretin; Amyloidosis; Cardiomyopathy; Disease; Restrictive cardiomyopathy; Cardiac amyloidosis; Cardiology; Internal medicine; Heart failure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001334309,0.0003898368,0.001091403,0.0005533722,0.000303217,0.0007980628,0.0003800519,0.0005340231,0.0007904145],"category_scores_gemma":[0.002527692,0.0001085432,0.001084122,0.000660642,0.0001717652,0.0005018254,0.0004410721,0.0009326618,0.0001621774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008837251,"about_ca_system_score_gemma":0.00049572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002333064,"about_ca_topic_score_gemma":0.004059361,"domain_scores_codex":[0.9991191,0.0002605203,0.0001043959,0.0001527372,0.0001970303,0.0001661291],"domain_scores_gemma":[0.9971966,0.0005729074,0.001208407,0.0001861953,0.0003245526,0.0005113985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02590963,0.001430126,0.8768,0.0002573354,0.002142595,0.000243315,0.0001931674,0.0009190803,0.001477872,0.0001092874,0.001242982,0.08927466],"study_design_scores_gemma":[0.0002599193,0.002230326,0.9943533,0.00006664397,0.0006306858,0.0002429276,0.00009597043,0.0007120945,0.000429742,0.0002035012,0.0007440634,0.00003072101],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939929,0.003113767,0.000209763,0.000319251,0.00005766278,0.00003002034,0.000865505,0.00001992453,0.001391152],"genre_scores_gemma":[0.9982716,0.0003907127,0.0001202575,0.00009998482,0.00007161086,0.00002556134,0.0007295431,0.000002769466,0.0002879825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002333064,"threshold_uncertainty_score":0.007056594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02066459921963271,"score_gpt":0.2730295436036593,"score_spread":0.2523649443840266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}