{"id":"W4388271273","doi":"10.1016/j.jcjd.2023.10.030","title":"KNOCKDOWN OF ADIPOR1 PROMOTES ADIPONECTIN'S ANTI-INFLAMMATORY ACTIONS MEDIATED THROUGH ADIPOR2 IN THP-1 MACROPHAGES","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Adiponectin; Adiponectin receptor 1; Gene knockdown; Medicine; Adipose tissue; Receptor; Macrophage; Inflammation; Monocyte; Inflammatory response; Endocrinology; Internal medicine; Cell biology; Cell culture; Biology; In vitro; Insulin; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003632812,0.0004865341,0.0005759441,0.0002793395,0.000399118,0.0004911132,0.0003017903,0.0004030836,0.00264212],"category_scores_gemma":[0.000142331,0.0003294767,0.0005948288,0.0004226285,0.0004346531,0.0003702881,0.0003139192,0.001222848,0.000782556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003380236,"about_ca_system_score_gemma":0.0005079846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002025078,"about_ca_topic_score_gemma":0.00310619,"domain_scores_codex":[0.9995241,0.00005466398,0.00007088638,0.00007853901,0.00008833471,0.0001835009],"domain_scores_gemma":[0.9998615,0.00002330322,0.00003087793,0.00002015545,0.00002166602,0.00004252702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001206867,0.0001169165,0.0003104559,0.0001888857,0.00003009051,0.0001439496,0.00008845537,0.0001471398,0.9957758,0.0002500414,0.0003803431,0.001361101],"study_design_scores_gemma":[0.0002146561,0.0006018549,0.00853276,0.00002271537,0.0001192327,0.000280256,0.0003553533,0.001986942,0.9812661,0.0001140241,0.006482161,0.00002391849],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865928,0.002279064,0.003584349,0.0006054718,0.0002465171,0.0000631595,0.002931428,0.0001926393,0.003504546],"genre_scores_gemma":[0.9854053,0.001707747,0.00307074,0.0003468947,0.00004057867,0.0001369951,0.001970565,0.000040685,0.007280679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00264212,"threshold_uncertainty_score":0.008838773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01833311702126958,"score_gpt":0.2650816538097518,"score_spread":0.2467485367884822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}