{"id":"W4388271273","doi":"10.1016/j.jcjd.2023.10.030","title":"KNOCKDOWN OF ADIPOR1 PROMOTES ADIPONECTIN'S ANTI-INFLAMMATORY ACTIONS MEDIATED THROUGH ADIPOR2 IN THP-1 MACROPHAGES","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Adiponectin; Adiponectin receptor 1; Gene knockdown; Medicine; Adipose tissue; Receptor; Macrophage; Inflammation; Monocyte; Inflammatory response; Endocrinology; Internal medicine; Cell biology; Cell culture; Biology; In vitro; Insulin; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004627345,0.0001726444,0.0003095055,0.0005289658,0.00008092058,0.00003007482,0.0003753063,0.0001879498,0.0001207676],"category_scores_gemma":[0.000908372,0.0001665232,0.0001449409,0.000599409,0.0002157835,0.0000268805,0.00004330186,0.0003021724,0.00002736825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006205025,"about_ca_system_score_gemma":0.00130713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004407161,"about_ca_topic_score_gemma":0.00734348,"domain_scores_codex":[0.9983689,0.0001262568,0.0004869025,0.0002040178,0.0002188293,0.0005951571],"domain_scores_gemma":[0.9987512,0.00009209051,0.0002401341,0.0002570657,0.0002715689,0.0003879914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007436703,0.00002110401,0.3251161,0.00009156352,0.0001745591,0.00005380292,0.0002008242,0.0001214245,0.6699156,0.0000217999,0.00388291,0.0003929541],"study_design_scores_gemma":[0.0007997365,0.0005110648,0.4533665,0.0002298654,0.00003267816,0.00001407648,0.0002197229,0.00006096191,0.5342969,0.0001546513,0.0100483,0.0002656365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971617,0.001662509,0.000002743917,0.0004009334,0.0001960497,0.0001578774,0.0001041832,0.000007804637,0.0003062188],"genre_scores_gemma":[0.9993718,0.00007213553,0.00008555286,0.00003899009,0.0001464042,0.000007421824,0.00005413853,0.00003820244,0.00018534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1356187,"threshold_uncertainty_score":0.679062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01833311702126958,"score_gpt":0.2650816538097518,"score_spread":0.2467485367884822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}