{"id":"W4388303079","doi":"10.22541/au.169898456.60178975/v1","title":"Anaphylactic Reactions Caused by the Covid-19 Vaccine Comirnaty in Anti-PEG Hyperimmune Pigs: Implications for the Safety of mRNA-LNP-based Vaccines and Other PEGylated Nanopharmaceuticals","year":2023,"lang":"en","type":"preprint","venue":"","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centracare","funders":"","keywords":"Medicine; Anaphylaxis; Immunology; Antibody; Pharmacology; Immune system; Allergy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006392919,0.0004113711,0.0002690515,0.0001318881,0.0001340023,0.0002553295,0.0001489001,0.0006891526,0.001004626],"category_scores_gemma":[0.0003103941,0.0001218527,0.0003481414,0.00006220015,0.0003665328,0.0003161532,0.0001490436,0.0007967846,0.0001751119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002902812,"about_ca_system_score_gemma":0.0001191405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001480488,"about_ca_topic_score_gemma":0.0001237573,"domain_scores_codex":[0.9997661,0.00008798199,0.00001737415,0.00004442192,0.00002738374,0.00005668834],"domain_scores_gemma":[0.9997105,0.00009737417,0.00009763006,0.00002967757,0.00002176289,0.00004297044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002941528,0.001208338,0.01356266,0.0002374732,0.0000259395,0.001144383,0.0001341295,0.0002815635,0.9728804,0.0001008895,0.0001320526,0.007350689],"study_design_scores_gemma":[0.0005243102,0.09298306,0.1836104,0.0001015775,0.000178825,0.008218974,0.0005015223,0.003768866,0.7066689,0.0002646287,0.003132736,0.00004615996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998359,0.0002636913,0.0007257828,0.00006501991,0.00001985461,0.00005333545,0.00004423494,0.00001403124,0.0004550098],"genre_scores_gemma":[0.9985495,0.0002745137,0.00053165,0.0001369698,0.00002532083,0.00005369515,0.000111111,0.000002719492,0.0003143896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001004626,"threshold_uncertainty_score":0.003380954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1293513488956,"score_gpt":0.4344397737971141,"score_spread":0.3050884249015141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}