{"id":"W4388317548","doi":"10.1016/b978-0-323-91338-6.00051-3","title":"Vitamin D mechanisms of protection in multiple sclerosis","year":2023,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Vitamin D Research Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Multiple sclerosis; Mendelian randomization; Vitamin D and neurology; Epigenetics; Biology; Oligodendrocyte; Myelin; FOXP3; Immunology; Gene; Neuroscience; Genetics; Immune system; Endocrinology; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002601483,0.0005318878,0.0004314299,0.001631178,0.0003898023,0.001509232,0.0004936824,0.001121418,0.05988394],"category_scores_gemma":[0.000298318,0.0002438854,0.0002241153,0.001224048,0.000460436,0.001149119,0.0006904911,0.0009746946,0.01508761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005832618,"about_ca_system_score_gemma":0.0004516648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001741039,"about_ca_topic_score_gemma":0.005145019,"domain_scores_codex":[0.9999269,0.00001481833,0.000004974721,0.000009076188,0.00003881756,0.000005299235],"domain_scores_gemma":[0.9998782,0.00008847038,0.000005481646,0.000006937623,0.00001330862,0.000007618326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000808086,0.00007063297,0.0001210081,0.001052159,0.00001419382,0.0002091778,0.0001667103,0.0002297476,0.002822888,0.06247164,0.3664979,0.5662631],"study_design_scores_gemma":[0.000009552328,0.00002928677,0.0002727715,0.000287438,0.000005234393,0.0002318402,0.00003976502,0.00004229821,0.0003432817,0.01141946,0.9873151,0.000004012775],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.0008251098,0.4383774,0.002188089,0.005747747,0.004637239,0.00003360922,0.0002730057,0.0001664775,0.5477514],"genre_scores_gemma":[0.003554995,0.1523592,0.001778634,0.001929506,0.002238711,0.00004291606,0.0001433489,0.00004950261,0.8379031],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.05988394,"threshold_uncertainty_score":0.2003318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0739007429633635,"score_gpt":0.2766668459046116,"score_spread":0.2027661029412481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}