{"id":"W4388347846","doi":"10.1016/j.jmb.2023.168344","title":"Antibody and B-cell Immune Responses Against Bordetella Pertussis Following Infection and Immunization","year":2023,"lang":"en","type":"review","venue":"Journal of Molecular Biology","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Nova Scotia Health Authority; Izaak Walton Killam Health Centre; Dalhousie University; BC Children's Hospital; University of British Columbia","funders":"Medical Research Council; European Research Council; Horizon 2020 Framework Programme; Michael Smith Health Research BC; BC Children’s Hospital Foundation","keywords":"Bordetella pertussis; Immunization; Immunology; Immunity; Antibody; Immune system; Biology; Pertussis toxin; B cell; Pertussis vaccine; Avidity; Humoral immunity; Vaccination; Whooping cough; Virology; Bacteria; G protein; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006047388,0.0009253492,0.001102183,0.001144985,0.0001445856,0.0005618125,0.0006351609,0.001201761,0.002214754],"category_scores_gemma":[0.0005874769,0.0002381227,0.0002650339,0.0008333852,0.0003601036,0.0007919503,0.0005446587,0.001355419,0.002054278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005182173,"about_ca_system_score_gemma":0.0007274589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004615031,"about_ca_topic_score_gemma":0.0008637382,"domain_scores_codex":[0.9998498,0.00002250806,0.0000202108,0.00001848245,0.00006706025,0.00002178062],"domain_scores_gemma":[0.9998282,0.00005980868,0.00003368293,0.000005545224,0.00005078056,0.00002183622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002858214,0.00009465699,0.0001281062,0.009071581,0.00004301386,0.0001914806,0.00002244706,0.000206472,0.005028866,0.001408014,0.04241049,0.9411091],"study_design_scores_gemma":[0.00006951157,0.0002960736,0.001414205,0.002243405,0.0001274646,0.001106305,0.00002564331,0.00007606895,0.002396164,0.001143964,0.9910871,0.00001407192],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002562137,0.9971624,0.0002159228,0.0004822362,0.0007452381,0.000009315822,0.0000232186,0.000009801725,0.001095658],"genre_scores_gemma":[0.001072426,0.9961035,0.0001847574,0.0004036337,0.0006632989,0.00001946343,0.00004613802,0.000001739045,0.001505055],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002214754,"threshold_uncertainty_score":0.007409096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02204141844136578,"score_gpt":0.3427759861156232,"score_spread":0.3207345676742574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}