{"id":"W4388365350","doi":"10.1016/j.ibneur.2023.08.756","title":"INSULIN PROMOTES RGC DENDRITE REGENERATION THROUGH RIBOSOMAL PROTEIN S6 KINASE ACTIVATION LEADING TO RESTORATION OF NEURONAL FUNCTION IN GLAUCOMA","year":2023,"lang":"en","type":"article","venue":"IBRO Neuroscience Reports","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Glaucoma; Regeneration (biology); Dendrite (mathematics); Cell biology; Ribosomal protein; Function (biology); Neuroscience; Biology; RNA; Biochemistry; Ribosome; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003157307,0.0001320121,0.0001199146,0.0001510512,0.0001237194,0.00004525564,0.00009217657,0.00009117558,0.000002604079],"category_scores_gemma":[0.0006251746,0.0001347093,0.00004405089,0.0008711069,0.00005541413,0.00007449504,0.00008732027,0.00008605537,0.000003386826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000224099,"about_ca_system_score_gemma":0.0001177459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004264264,"about_ca_topic_score_gemma":0.00004498246,"domain_scores_codex":[0.9984285,0.0000797959,0.000389572,0.0005613803,0.0003013095,0.0002394673],"domain_scores_gemma":[0.9993191,0.000006393643,0.0002226715,0.0003056881,0.00009172073,0.00005445283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006138338,0.00005620343,0.005889423,0.00001815637,8.756395e-7,0.00002982553,0.00003936897,0.0006008174,0.9918845,0.0001529173,0.00010762,0.001158877],"study_design_scores_gemma":[0.0001242217,0.0005883683,0.06691717,0.00004450469,0.000002168829,0.00002465962,0.0000162161,0.0004979459,0.9284667,0.000277435,0.002909358,0.0001312307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945039,0.00001567338,0.003951582,0.0004853956,0.0002952421,0.0006125268,0.000003351956,0.00003655885,0.00009572897],"genre_scores_gemma":[0.9987686,0.000007245349,0.0003605246,0.0001740403,0.0001288455,0.00009942446,0.00005964607,0.00001742703,0.0003841965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06341781,"threshold_uncertainty_score":0.5493287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02530413225544522,"score_gpt":0.2773188644781848,"score_spread":0.2520147322227396,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}