{"id":"W4388365350","doi":"10.1016/j.ibneur.2023.08.756","title":"INSULIN PROMOTES RGC DENDRITE REGENERATION THROUGH RIBOSOMAL PROTEIN S6 KINASE ACTIVATION LEADING TO RESTORATION OF NEURONAL FUNCTION IN GLAUCOMA","year":2023,"lang":"en","type":"article","venue":"IBRO Neuroscience Reports","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Glaucoma; Regeneration (biology); Dendrite (mathematics); Cell biology; Ribosomal protein; Function (biology); Neuroscience; Biology; RNA; Biochemistry; Ribosome; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001149405,0.0001673167,0.0001734538,0.0002056424,0.0001133961,0.0001503466,0.00008020379,0.0001611546,0.0009106675],"category_scores_gemma":[0.00007428683,0.00007840334,0.0001854928,0.0001139375,0.0001822192,0.0001581491,0.0001144097,0.0004599314,0.0001984921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002294391,"about_ca_system_score_gemma":0.0001275738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005819305,"about_ca_topic_score_gemma":0.001362715,"domain_scores_codex":[0.9999399,0.000008400456,0.000006481893,0.00001064928,0.00001610248,0.00001844161],"domain_scores_gemma":[0.9999555,0.00000511785,0.00001303483,0.000004037578,0.000003604214,0.0000187241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001933833,0.00002556286,0.0002083083,0.00003345319,0.000003299427,0.00006567068,0.00001349814,0.00001621047,0.9981121,0.00006788691,0.00005605931,0.001204679],"study_design_scores_gemma":[0.00007263791,0.0006403135,0.02517582,0.00001138012,0.00002706183,0.0004423724,0.00007380833,0.0006401349,0.9701434,0.0001205897,0.002645332,0.000007173099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995699,0.001590941,0.0006993591,0.0001857902,0.00004238226,0.0000155322,0.0001081418,0.00006928556,0.001589575],"genre_scores_gemma":[0.9961211,0.001132962,0.001000408,0.00006995818,0.00001970068,0.00001750331,0.00009100464,0.0000144036,0.001532922],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009106675,"threshold_uncertainty_score":0.003046513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02530413225544522,"score_gpt":0.2773188644781848,"score_spread":0.2520147322227396,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}