{"id":"W4388383236","doi":"10.1016/j.dnarep.2023.103591","title":"Telomeres as hotspots for innate immunity and inflammation","year":2023,"lang":"en","type":"article","venue":"DNA repair","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Hewitt Foundation; National Institute on Aging; Samuel Waxman Cancer Research Foundation; National Institute of General Medical Sciences; American Heart Association; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; European Molecular Biology Organization; Glenn Foundation for Medical Research; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Telomere; Biology; Inflammation; Innate immune system; Immunity; Senescence; Immunology; Permissive; Neuroscience; Genetics; Immune system; DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008428675,0.0003134643,0.0004920175,0.0009382475,0.0004239286,0.001877409,0.0003569785,0.001023252,0.002598167],"category_scores_gemma":[0.00073734,0.0001937371,0.0002651926,0.0004842703,0.0007014922,0.001134883,0.0009454312,0.001140788,0.0003668848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003498644,"about_ca_system_score_gemma":0.0003482351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001705759,"about_ca_topic_score_gemma":0.0004065277,"domain_scores_codex":[0.9996425,0.0001009644,0.00002511666,0.00005874027,0.00008640835,0.00008628145],"domain_scores_gemma":[0.9995275,0.0001074148,0.0001475296,0.00004172332,0.00004916063,0.0001267369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00494462,0.0002806551,0.06006912,0.002977988,0.0007193814,0.00297341,0.003878433,0.001890398,0.5165631,0.0998054,0.01886633,0.2870312],"study_design_scores_gemma":[0.0005890668,0.003336116,0.2915358,0.002113478,0.00103004,0.01173876,0.01146342,0.004253311,0.1684073,0.1503686,0.3548698,0.0002943705],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.4571969,0.5162373,0.00581558,0.008050034,0.001188686,0.00002666627,0.0003606337,0.0002638471,0.01086043],"genre_scores_gemma":[0.9429757,0.04819661,0.001439336,0.0009324469,0.001234311,0.00001792212,0.0001142939,0.00002162051,0.005067825],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002598167,"threshold_uncertainty_score":0.008691728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02334003241290473,"score_gpt":0.297398092090955,"score_spread":0.2740580596780503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}