{"id":"W4388447779","doi":"10.1109/ius51837.2023.10306524","title":"Ultrasound targeted VS1-loaded microbubbles for oncolytic virotherapy of breast cancer","year":2023,"lang":"en","type":"article","venue":"","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Université de Montréal","funders":"Government of Canada","keywords":"Oncolytic virus; Microbubbles; Virotherapy; Mononuclear phagocyte system; Cancer research; Immune system; Lysis; Ultrasound; Biology; Tumor cells; Medicine; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001166506,0.0001947203,0.0001888808,0.0001753001,0.0001111234,0.0001758473,0.0001483628,0.0002978812,0.0008332089],"category_scores_gemma":[0.0001038225,0.0001012884,0.0001332306,0.0001096731,0.0001589577,0.0002070035,0.0002089333,0.0003810732,0.0002322885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002860223,"about_ca_system_score_gemma":0.0002273423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006938305,"about_ca_topic_score_gemma":0.0008816213,"domain_scores_codex":[0.9999492,0.00001168149,0.000002211783,0.00001219097,0.00001348023,0.00001122254],"domain_scores_gemma":[0.9999692,0.000008496081,0.000009456629,0.000001708457,0.000004065167,0.000007068868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009435469,0.00002251493,0.00004138421,0.0000932935,0.000003788999,0.00003425046,0.00003444435,0.0003437239,0.9931972,0.000263258,0.000099047,0.005772756],"study_design_scores_gemma":[0.00001790521,0.0002878802,0.0003186689,0.000006851587,0.0000141724,0.0001093375,0.00001110605,0.002398968,0.9934216,0.00003960605,0.003368148,0.000005741512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9641707,0.01143339,0.02082966,0.0003542977,0.00009913671,0.0001162418,0.0001129722,0.0002359367,0.002647632],"genre_scores_gemma":[0.9841774,0.003500982,0.008871975,0.00008883324,0.00002268991,0.00007255164,0.00008633553,0.00003758048,0.003141789],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008332089,"threshold_uncertainty_score":0.002787352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02020749376637222,"score_gpt":0.3239599466428247,"score_spread":0.3037524528764525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}