{"id":"W4388459601","doi":"10.3389/fphar.2023.1301423","title":"Antihypertensive medications and risk of colorectal cancer in British Columbia","year":2023,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Colorectal Cancer Screening and Detection","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Michael Smith Health Research BC","keywords":"Medicine; Colorectal cancer; Hazard ratio; Internal medicine; Proportional hazards model; Cohort; Retrospective cohort study; Oncology; Cohort study; Cancer; Cumulative dose; Confidence interval","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004039411,0.0002032602,0.0003404399,0.001111982,0.0008864119,0.0008941648,0.0008246829,0.000355191,0.002730508],"category_scores_gemma":[0.002044773,0.000291344,0.0003421333,0.003192016,0.0002978051,0.0001746151,0.0004351896,0.0005082238,0.0003411511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004653882,"about_ca_system_score_gemma":0.006659351,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9246854,"about_ca_topic_score_gemma":0.946435,"domain_scores_codex":[0.9994965,0.00005691168,0.00005054401,0.0001101615,0.0001901332,0.00009575528],"domain_scores_gemma":[0.9982896,0.000208719,0.00050747,0.0001130056,0.0006304389,0.0002506444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00006826108,0.00001420359,0.9936876,0.0001222627,0.0001283692,0.00009973768,0.0001060819,0.00009353534,0.0001615204,0.00003483513,0.001293991,0.004189567],"study_design_scores_gemma":[0.000009134088,0.00001019382,0.9981425,0.00007348274,0.00005746281,0.00009745239,0.0001065696,0.0001718777,0.00004015907,0.00002375843,0.001261987,0.000005385136],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.970037,0.007013861,0.0003380563,0.000776086,0.00005383371,0.00006424981,0.0162713,0.00004988614,0.005395715],"genre_scores_gemma":[0.9910409,0.002761445,0.0003301098,0.000243449,0.00001803795,0.00002786897,0.004035417,0.000008675952,0.001534095],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07531464,"threshold_uncertainty_score":0.1515163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009303162218795222,"score_gpt":0.2834643413882077,"score_spread":0.2741611791694125,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}