{"id":"W4388477717","doi":"10.5376/jmr.2023.13.0001","title":"Application of CRISPRCas9 in Gene Editing of &lt;i&gt;Aedes aegypti&lt;/i&gt; Mosquitoes: Methods and Challenges","year":2023,"lang":"en","type":"article","venue":"Journal of Mosquito Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Aedes aegypti; CRISPR; Genome editing; Dengue fever; Biology; Yellow fever; Cas9; Aedes; Zika virus; Malaria; Virology; Ecology; Virus; Gene; Genetics; Immunology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001464544,0.0004586509,0.0007821155,0.0006506094,0.0003836327,0.001219611,0.0005411026,0.0008224354,0.001721243],"category_scores_gemma":[0.001117102,0.0002921654,0.0007417879,0.0004749962,0.0005996056,0.0008909632,0.0005650858,0.001245178,0.00065856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005387879,"about_ca_system_score_gemma":0.001168186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001564489,"about_ca_topic_score_gemma":0.002049683,"domain_scores_codex":[0.9990872,0.0002255378,0.0001296291,0.00017375,0.0003103737,0.0000735678],"domain_scores_gemma":[0.9994211,0.0002947199,0.00008468106,0.00004579053,0.0001257531,0.00002782115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000217683,0.00007706408,0.002370462,0.0159572,0.0002719611,0.001557743,0.0005208728,0.002686505,0.3696273,0.01746262,0.01397751,0.5752732],"study_design_scores_gemma":[0.00003475907,0.0005309902,0.003517189,0.001984079,0.0003570194,0.005514061,0.0003289927,0.002800967,0.2366644,0.005254583,0.7429009,0.0001120472],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04664168,0.7668784,0.1397606,0.007409405,0.00231508,0.0003863046,0.001014378,0.0007162315,0.03487799],"genre_scores_gemma":[0.2181578,0.6722533,0.0924612,0.003004712,0.0003438939,0.0003150371,0.0009970914,0.0001652107,0.01230183],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001721243,"threshold_uncertainty_score":0.007745326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06482243572440358,"score_gpt":0.4453343689571215,"score_spread":0.3805119332327179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}