{"id":"W4388494972","doi":"10.1136/ijgc-2023-igcs.80","title":"PR038/#248  Management of immune-related adverse events in patients with primary advanced or recurrent endometrial cancer: dostarlimab plus chemotherapy compared with chemotherapy alone in the ENGOT-EN6-NSGO/GOG-3031/RUBY trial","year":2023,"lang":"en","type":"article","venue":"International Journal of Gynecological Cancer","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Carboplatin; Medicine; Paclitaxel; Placebo; Internal medicine; Chemotherapy; Adverse effect; Endometrial cancer; Oncology; Urology; Surgery; Cancer; Cisplatin; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001079215,0.0007016486,0.001880399,0.0002095959,0.0001928774,0.0008185309,0.0005791315,0.0008433094,0.004649044],"category_scores_gemma":[0.0009518148,0.0002985482,0.002000269,0.0002694049,0.0005437609,0.0006931518,0.0002980625,0.002612342,0.0008170592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005234036,"about_ca_system_score_gemma":0.0006720152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006900142,"about_ca_topic_score_gemma":0.002392039,"domain_scores_codex":[0.999615,0.0002118442,0.00002343349,0.00005240902,0.00003028932,0.00006704104],"domain_scores_gemma":[0.9996069,0.000104687,0.00009041656,0.00003075198,0.00002019859,0.0001470335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8309216,0.003308313,0.004902004,0.001472064,0.004079734,0.0001497171,0.00008117978,0.001589768,0.005672031,0.0005571384,0.004959007,0.1423075],"study_design_scores_gemma":[0.7920996,0.1730602,0.02200172,0.0002372244,0.003277403,0.0003261111,0.000101284,0.001782422,0.001091242,0.0009592689,0.005010407,0.00005306808],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9720447,0.01659667,0.0004899552,0.002431665,0.0006654981,0.0005598677,0.001199276,0.0001548932,0.005857496],"genre_scores_gemma":[0.9895431,0.003692686,0.000658511,0.001593647,0.0003470316,0.0004002824,0.001046025,0.00002490567,0.002693828],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004649044,"threshold_uncertainty_score":0.01555258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02211874238495013,"score_gpt":0.3155145385664933,"score_spread":0.2933957961815431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}