{"id":"W4388498274","doi":"10.1136/ijgc-2023-igcs.413","title":"EP358/#615  Methylation profiling identifies two distinct clusters of small cell carcinoma of the ovary hypercalcemic type (SCCOHT)","year":2023,"lang":"en","type":"article","venue":"International Journal of Gynecological Cancer","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; University of Alberta; McGill University Health Centre","funders":"Ajou University","keywords":"Biology; Malignancy; DNA methylation; Ovarian carcinoma; Oncology; Breakpoint; Internal medicine; Ovarian cancer; Medicine; Cancer; Genetics; Chromosomal translocation; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003256024,0.0000879836,0.000161958,0.00005661773,0.00002895631,0.00001009798,0.0003875048,0.00008156893,0.00006647361],"category_scores_gemma":[0.0002962041,0.00005819695,0.0001785821,0.0001242934,0.0000845688,0.00000649771,0.0001466209,0.0001260053,0.000001482237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006280508,"about_ca_system_score_gemma":0.0001921507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005634096,"about_ca_topic_score_gemma":0.00005364269,"domain_scores_codex":[0.9989657,0.00007315537,0.0004399234,0.0001243587,0.000290565,0.000106259],"domain_scores_gemma":[0.9987189,0.00008473793,0.000450994,0.0001101002,0.0006038572,0.00003143242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003495042,0.00007035173,0.06531392,0.00003908688,0.0001392263,0.00000754135,0.0000894211,0.01724855,0.9124382,0.00002410738,0.0007359959,0.003544047],"study_design_scores_gemma":[0.001331723,0.0003639238,0.1484511,0.00008089164,0.00008546998,0.00002521049,0.0001932543,0.003756197,0.8442734,0.0005553835,0.0007334097,0.0001499765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968927,0.0007891117,0.0003485735,0.0002434167,0.001306009,0.00007644622,0.00002521646,0.000003478458,0.0003150413],"genre_scores_gemma":[0.9987944,0.0002245869,0.0003213941,0.00009208379,0.0002820581,0.000004247102,0.00001519249,0.000008765472,0.0002572666],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08313722,"threshold_uncertainty_score":0.2373203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03080369130968388,"score_gpt":0.311248810703695,"score_spread":0.2804451193940111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}