{"id":"W4388510210","doi":"10.1016/j.celrep.2023.113407","title":"Single-cell resolution of the adult zebrafish intestine under conventional conditions and in response to an acute Vibrio cholerae infection","year":2023,"lang":"en","type":"article","venue":"Cell Reports","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; Li Ka Shing Institute of Virology, University of Alberta; Natural Sciences and Engineering Research Council of Canada; University Hospital Foundation; Canadian Institutes of Health Research; Alberta Innovates; Canada Foundation for Innovation; University of Alberta","keywords":"Vibrio cholerae; Zebrafish; Biology; Microbiology; Immune system; Pathogen; Vibrio; Interferon; Transcriptome; Population; Cell biology; Bacteria; Immunology; Gene; Genetics; Gene expression; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007821001,0.0001724512,0.0001576693,0.0002561187,0.0002205904,0.000210617,0.0001665432,0.0003071724,0.001341946],"category_scores_gemma":[0.00007073087,0.0001332247,0.000163869,0.0001309133,0.0002469245,0.0001544346,0.0002894403,0.0005970294,0.0004568036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004144397,"about_ca_system_score_gemma":0.0002103284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003310183,"about_ca_topic_score_gemma":0.009871369,"domain_scores_codex":[0.9999465,0.000001663106,0.000002793296,0.00001730089,0.00001612608,0.00001575108],"domain_scores_gemma":[0.9999382,0.00000710461,0.00001244637,0.000004640829,0.00001530392,0.00002230836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001623526,0.000002292477,0.0003621113,0.0000121239,0.000001018954,0.0000251431,0.00001976677,0.00002052265,0.9991881,0.00003026937,0.00003236521,0.0002899358],"study_design_scores_gemma":[0.00002809182,0.0002702082,0.2120654,0.00003298845,0.00003145301,0.0005481374,0.0005360419,0.003859005,0.7755086,0.000331378,0.006762344,0.00002649468],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.980451,0.001009829,0.00891446,0.0002174367,0.00005773109,0.0000722793,0.004170374,0.0001913583,0.004915503],"genre_scores_gemma":[0.974826,0.0007741693,0.01119542,0.0003357546,0.00002427834,0.0001666485,0.002371142,0.00009092782,0.01021561],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003310183,"threshold_uncertainty_score":0.006581783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01652978347361549,"score_gpt":0.2800486796903137,"score_spread":0.2635188962166982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}