{"id":"W4388524023","doi":"10.1016/j.anai.2023.10.019","title":"FAST SYMPTOM IMPROVEMENT AND FAVORABLE SAFETY PROFILE WITH REMIBRUTINIB IN CHRONIC SPONTANEOUS URTICARIA: REMIX-1/-2 STUDIES","year":2023,"lang":"en","type":"article","venue":"Annals of Allergy Asthma & Immunology","topic":"Urticaria and Related Conditions","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"North York General Hospital","funders":"","keywords":"Placebo; Medicine; Adverse effect; Clinical endpoint; Internal medicine; Randomized controlled trial; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002485107,0.000236863,0.0006083478,0.0003155945,0.0001221726,0.000007837646,0.0001142641,0.0002371817,0.0001470345],"category_scores_gemma":[0.0001030674,0.0001865266,0.00008867079,0.0005498909,0.0004824272,0.00007822394,0.0001583416,0.0004055644,0.00005917518],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009736357,"about_ca_system_score_gemma":0.0003205965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001303362,"about_ca_topic_score_gemma":0.0002162878,"domain_scores_codex":[0.9981843,0.0000774957,0.0005410733,0.0004173569,0.0001867042,0.0005930766],"domain_scores_gemma":[0.9989734,0.0001356826,0.0001507472,0.0004150643,0.0002438164,0.00008127121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01265387,0.001754083,0.0007809169,0.0004718014,0.06845487,0.01212061,0.01127513,0.001717371,0.7286782,0.0818997,0.00940288,0.07079058],"study_design_scores_gemma":[0.0481841,0.0652131,0.4210393,0.007254166,0.001001648,0.01277789,0.04031971,0.004123835,0.1668578,0.0122124,0.2172534,0.003762651],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9776024,0.01009164,0.00001705221,0.008894658,0.0001619291,0.000518336,0.00002637052,0.0001291711,0.002558425],"genre_scores_gemma":[0.9707556,0.02544612,0.0002109268,0.0002444275,0.0000639756,0.00008419251,0.0001265543,0.00004143699,0.003026727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5618204,"threshold_uncertainty_score":0.7606332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02187460675515764,"score_gpt":0.2924118550071194,"score_spread":0.2705372482519617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}