{"id":"W4388524023","doi":"10.1016/j.anai.2023.10.019","title":"FAST SYMPTOM IMPROVEMENT AND FAVORABLE SAFETY PROFILE WITH REMIBRUTINIB IN CHRONIC SPONTANEOUS URTICARIA: REMIX-1/-2 STUDIES","year":2023,"lang":"en","type":"article","venue":"Annals of Allergy Asthma & Immunology","topic":"Urticaria and Related Conditions","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"North York General Hospital","funders":"","keywords":"Placebo; Medicine; Adverse effect; Clinical endpoint; Internal medicine; Randomized controlled trial; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001667001,0.000852403,0.001539746,0.0002231622,0.0003111728,0.0006312046,0.0004031718,0.0005434199,0.003267024],"category_scores_gemma":[0.000834599,0.0002110124,0.001750692,0.0002065207,0.0004399866,0.0007139923,0.0001920181,0.001912356,0.0005811055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000364474,"about_ca_system_score_gemma":0.0003752549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002785802,"about_ca_topic_score_gemma":0.0008325998,"domain_scores_codex":[0.9996341,0.0001473033,0.00002977685,0.00005127051,0.000043575,0.00009386295],"domain_scores_gemma":[0.9995686,0.0001209782,0.0001061074,0.00007124041,0.00002971056,0.0001034282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3694734,0.02247051,0.01314616,0.003652021,0.005546394,0.001028133,0.0003621247,0.002339997,0.1475138,0.0006830462,0.005283029,0.4285012],"study_design_scores_gemma":[0.2756854,0.5759377,0.08473826,0.0003136744,0.00501826,0.00353911,0.0001854658,0.002186169,0.03202198,0.0008170024,0.01942044,0.0001364877],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807591,0.01421876,0.0008072089,0.0004792922,0.0001233032,0.0004304359,0.0007778137,0.0001094372,0.002294534],"genre_scores_gemma":[0.9929716,0.003586416,0.0006927924,0.0004831367,0.0001608664,0.0002024866,0.0008611245,0.00003050459,0.00101111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003267024,"threshold_uncertainty_score":0.01092929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02187460675515764,"score_gpt":0.2924118550071194,"score_spread":0.2705372482519617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}