{"id":"W4388526317","doi":"10.3390/cells12222594","title":"The Multifunctional Nature of the MicroRNA/AKT3 Regulatory Axis in Human Cancers","year":2023,"lang":"en","type":"review","venue":"Cells","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"AKT3; microRNA; Protein kinase B; Biology; Cancer research; Carcinogenesis; Metastasis; AKT1; AKT2; PI3K/AKT/mTOR pathway; Cancer; Computational biology; Bioinformatics; Signal transduction; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003372499,0.0005529433,0.0007008257,0.0009463843,0.0001661682,0.0005632452,0.0003793146,0.0005296029,0.001642208],"category_scores_gemma":[0.0003005616,0.0001965511,0.0002693461,0.0009795569,0.0002782845,0.0006296812,0.0004393095,0.001158532,0.001237554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004165836,"about_ca_system_score_gemma":0.0007735685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004467227,"about_ca_topic_score_gemma":0.001000472,"domain_scores_codex":[0.9999064,0.00001399053,0.00001705747,0.00001852398,0.00003411926,0.000009964701],"domain_scores_gemma":[0.9999021,0.00004365075,0.00001519407,0.000002504466,0.00002549194,0.00001102135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006848211,0.0000343084,0.000205706,0.01138732,0.00007061419,0.0002484985,0.00005168526,0.000291449,0.005618264,0.00399893,0.01534428,0.9626805],"study_design_scores_gemma":[0.00001527276,0.00008880804,0.001016106,0.001275894,0.00009782823,0.001626848,0.00003516084,0.0001121342,0.001596653,0.001750733,0.9923671,0.00001746198],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002167155,0.9979448,0.0002523641,0.0002546278,0.0002001441,0.00000472751,0.00001947387,0.00001205339,0.001095067],"genre_scores_gemma":[0.001101566,0.9978957,0.0002484142,0.0001636629,0.0001228037,0.00000624075,0.00002688752,0.000001716522,0.0004329889],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001642208,"threshold_uncertainty_score":0.005493701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02001956481644391,"score_gpt":0.3224170796000734,"score_spread":0.3023975147836295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}