{"id":"W4388588439","doi":"10.1093/neuonc/noad179.0111","title":"CNSC-27. LOSS OF CAPICUA IMPAIRS OLIGODENDROGENESIS IN THE DEVELOPING MOUSE BRAIN","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Biology; PDGFRA; Oligodendrocyte; Molecular biology; Transcriptome; Cell biology; Lineage markers; Cancer research; Myelin; Gene expression; Neuroscience; Gene; Genetics; Stem cell; Central nervous system; Progenitor cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005028889,0.001343364,0.000636827,0.001561323,0.0004943066,0.000561211,0.0008354162,0.0008531734,0.006015855],"category_scores_gemma":[0.0001835949,0.0005266219,0.0008282129,0.0005410534,0.0008440555,0.000334342,0.0005435191,0.001759191,0.002799863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006692053,"about_ca_system_score_gemma":0.0008883131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002311138,"about_ca_topic_score_gemma":0.004017081,"domain_scores_codex":[0.9992037,0.00006164986,0.00008233392,0.0001800538,0.0002660361,0.0002063259],"domain_scores_gemma":[0.9991985,0.00004409332,0.0002390973,0.00007030051,0.00007377962,0.0003743206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002656417,0.0001445267,0.0002301448,0.0001379472,0.00001288007,0.0001990965,0.00004260371,0.0001709833,0.9963321,0.0003284055,0.0004438022,0.001691938],"study_design_scores_gemma":[0.00004487727,0.0004782405,0.004897856,0.00004627023,0.00004227675,0.0003666394,0.00006674742,0.001014287,0.9853687,0.00008458168,0.007574088,0.00001545242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9616807,0.003450829,0.007724233,0.0004195257,0.0002999275,0.0004000954,0.01404441,0.00129758,0.01068274],"genre_scores_gemma":[0.9370888,0.002755954,0.009345835,0.0003377329,0.00006626215,0.001127603,0.01181652,0.0007768656,0.03668449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006015855,"threshold_uncertainty_score":0.02012509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03412638087190769,"score_gpt":0.3197003617921852,"score_spread":0.2855739809202775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}