{"id":"W4388588461","doi":"10.1093/neuonc/noad179.0296","title":"CTNI-14. NEOADJUVANT STEREOTACTIC RADIOSURGERY (NASRS) FOR LARGE BRAIN METASTASES (BRM): RESULTS OF AN INTERNATIONAL MULTICENTER PHASE II TRIAL","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University Health Network; Toronto Western Hospital; Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; Radiosurgery; Clinical endpoint; Radiation therapy; Surgery; Lesion; Nuclear medicine; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002467964,0.001203656,0.00155747,0.000351124,0.0003484279,0.0009740244,0.0008299086,0.0009689342,0.002657334],"category_scores_gemma":[0.001309024,0.0003964771,0.001011668,0.0004975416,0.0009669256,0.0006730141,0.0002989053,0.002482534,0.0007414384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009703296,"about_ca_system_score_gemma":0.001803404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001464177,"about_ca_topic_score_gemma":0.005694632,"domain_scores_codex":[0.9992198,0.0005313297,0.00004323908,0.00008011531,0.00005405943,0.00007147934],"domain_scores_gemma":[0.9991227,0.0001403224,0.0002266509,0.00006647522,0.00006104368,0.0003828023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8456556,0.02538103,0.006217456,0.001138567,0.001519272,0.0001198176,0.0001387442,0.002180606,0.01802546,0.0003285567,0.004897754,0.09439717],"study_design_scores_gemma":[0.6537543,0.3221479,0.01375745,0.0001426008,0.001068753,0.000245637,0.00008280431,0.001515353,0.002780372,0.000298822,0.004160199,0.00004589061],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813998,0.008916051,0.000729316,0.001301615,0.000345628,0.002265446,0.001274312,0.000140522,0.003627344],"genre_scores_gemma":[0.9810394,0.006096441,0.00232132,0.001497493,0.0003635844,0.002752097,0.003002238,0.00004494567,0.002882537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002657334,"threshold_uncertainty_score":0.01305199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05529110521120137,"score_gpt":0.3893552114297121,"score_spread":0.3340641062185107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}