{"id":"W4388588799","doi":"10.1093/neuonc/noad179.0424","title":"DDDR-31. TARGETING CANCER STEM CELLS WITH A CDK2 INHIBITOR IN GLIOBLASTOMA","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Cancer research; Stem cell; CDK inhibitor; Cyclin-dependent kinase; Cancer stem cell; Biology; Cancer; Cell cycle; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001074146,0.0003450035,0.0004334813,0.0004903857,0.0001366939,0.0003172861,0.0002259948,0.0002265808,0.001297358],"category_scores_gemma":[0.00006054196,0.0001187526,0.0002250622,0.0003258397,0.0001349022,0.0001475244,0.000186469,0.0004259546,0.0003608058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004486275,"about_ca_system_score_gemma":0.000411053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002042464,"about_ca_topic_score_gemma":0.004657119,"domain_scores_codex":[0.9999366,0.000008311607,0.000006105273,0.00001240623,0.00001678555,0.00001978654],"domain_scores_gemma":[0.9999758,0.000003055268,0.000004603881,0.000002434862,0.000004202857,0.000009903847],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008179704,0.0005432536,0.0007252149,0.0003322617,0.00004468565,0.0002869026,0.00003528072,0.002178701,0.9636577,0.0004463584,0.001218483,0.02971313],"study_design_scores_gemma":[0.0004129116,0.0054506,0.004319507,0.0000306714,0.00007877911,0.0007748922,0.00003830139,0.004025071,0.9696627,0.0001679253,0.01501997,0.00001867727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9733387,0.0151244,0.002806205,0.0003859427,0.00009995842,0.0003034644,0.001424566,0.0002860135,0.006230855],"genre_scores_gemma":[0.9859218,0.006429789,0.002895501,0.0001706372,0.00001302061,0.0001028838,0.001330307,0.00002006298,0.003115926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002042464,"threshold_uncertainty_score":0.004340112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008996403821320255,"score_gpt":0.25389812578119,"score_spread":0.2449017219598698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}