{"id":"W4388589206","doi":"10.1093/neuonc/noad179.1190","title":"MODL-39. ELUCIDATING THE TRANSCRIPTOMIC LANDSCAPE OF METASTATIC PEDIATRIC MEDULLOBLASTOMA","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Medulloblastoma; Transcriptome; Biology; Wnt signaling pathway; Epigenetics; Gene; Disease; Cancer research; Bioinformatics; Computational biology; Genetics; Gene expression; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001397264,0.0002424507,0.0002963484,0.0004576388,0.0002399658,0.0004007297,0.0001341821,0.0001619473,0.001636639],"category_scores_gemma":[0.0001163304,0.000120007,0.0002372459,0.0004544577,0.0001715694,0.000145632,0.0001903055,0.0003806367,0.0005714311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000400192,"about_ca_system_score_gemma":0.0003544588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008538797,"about_ca_topic_score_gemma":0.001637543,"domain_scores_codex":[0.9998716,0.000007146055,0.000005449502,0.00004267798,0.00004064462,0.00003236787],"domain_scores_gemma":[0.9999319,0.00001100147,0.00002401549,0.000006115436,0.00001098247,0.00001604452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003932811,0.00003357945,0.007054836,0.0001620106,0.00002029743,0.0001777941,0.00005712133,0.0002618651,0.983884,0.0001738071,0.0004135714,0.007367818],"study_design_scores_gemma":[0.00008313596,0.001160865,0.2954629,0.00008979186,0.00020077,0.002333887,0.0006820221,0.007785589,0.637244,0.0007947925,0.05413198,0.00003034109],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9683636,0.004485084,0.004581595,0.0002492475,0.00005582927,0.00008482501,0.02000649,0.0001899087,0.001983352],"genre_scores_gemma":[0.9603425,0.002756885,0.007742349,0.0002153356,0.00003098239,0.0001580623,0.02507373,0.000105802,0.003574383],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001636639,"threshold_uncertainty_score":0.005475163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02852982910836686,"score_gpt":0.303704263540375,"score_spread":0.2751744344320081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}