{"id":"W4388589468","doi":"10.1093/neuonc/noad179.0377","title":"DNAR-11. NUCLEAR POTASSIUM GOVERNS NUCLEAR ENVELOPE INTEGRITY AND GENOMIC STRUCTURE IN MEDULLOBLASTOMA","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Potassium channel; Cell biology; Nuclear pore; Cytosol; Nuclear localization sequence; Biology; Potassium; Cell nucleus; Chemistry; Biophysics; Nucleus; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001040291,0.0001537385,0.0001455884,0.0001623144,0.000132225,0.0002247241,0.0001272956,0.0001760006,0.0008786864],"category_scores_gemma":[0.0001043896,0.00008732911,0.0001272438,0.00007625256,0.0002587709,0.0001793353,0.0001681673,0.0002765067,0.0002675938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005046086,"about_ca_system_score_gemma":0.0001839708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001150675,"about_ca_topic_score_gemma":0.001891933,"domain_scores_codex":[0.999913,0.00001042133,0.000007566241,0.00002218204,0.00002843233,0.00001839225],"domain_scores_gemma":[0.9998912,0.000006944439,0.00005770639,0.000007983903,0.00001010361,0.00002605159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005120625,0.00000457105,0.0005978653,0.00002015269,0.000002040121,0.00003984814,0.0000100048,0.00005151836,0.9985756,0.00009683934,0.0000165004,0.0005338911],"study_design_scores_gemma":[0.00001231531,0.0001819719,0.02735611,0.000008904218,0.00001784263,0.0005863555,0.00008836286,0.00166635,0.9675691,0.0001601493,0.002345992,0.000006434254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948274,0.001056252,0.002802132,0.00008610867,0.00001275233,0.00001092108,0.0002550406,0.00009972333,0.000849442],"genre_scores_gemma":[0.9985813,0.0001740251,0.0004846804,0.00001420564,0.000001224894,0.000003929376,0.00009536546,0.000008297193,0.0006370081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001150675,"threshold_uncertainty_score":0.003661215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01181358578915938,"score_gpt":0.2461379024006386,"score_spread":0.2343243166114792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}