{"id":"W4388590565","doi":"10.1093/neuonc/noad179.0472","title":"EPCO-08. CONVERGENCE OF NON-CODING SOMATIC MUTATIONS ON CANCER DRIVER PLEXUSES IN PEDIATRIC HIGH-GRADE GLIOMA","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Epigenetics; Biology; Pediatric cancer; Somatic cell; Genetics; Gene; Germline mutation; Glioma; Cancer; Mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004748425,0.0003468223,0.000281247,0.001946363,0.000423343,0.0008708066,0.0004279183,0.0004596519,0.01007034],"category_scores_gemma":[0.002328023,0.0001388548,0.0004618805,0.00224596,0.0001968313,0.0003997712,0.0007686451,0.0004165672,0.001368525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006142337,"about_ca_system_score_gemma":0.0009194349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004548266,"about_ca_topic_score_gemma":0.006293143,"domain_scores_codex":[0.999558,0.00004439277,0.00003824616,0.0001482949,0.0001353608,0.00007569765],"domain_scores_gemma":[0.9982194,0.0004893568,0.0005151923,0.000138468,0.000328487,0.0003091141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001257487,0.0001502399,0.8784586,0.0006917792,0.0005028587,0.001275207,0.0002059089,0.005430026,0.02802497,0.002439007,0.01475708,0.06680692],"study_design_scores_gemma":[0.00006852754,0.0002568128,0.936506,0.0001272515,0.0003618005,0.004017748,0.000321972,0.01941455,0.01032503,0.003575798,0.02499222,0.00003232923],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9144282,0.001958234,0.009397479,0.0007800895,0.0001266119,0.0000963297,0.06364388,0.0009623457,0.008606867],"genre_scores_gemma":[0.9283521,0.001108981,0.007538625,0.0002310133,0.00005190719,0.00009439573,0.06018448,0.000248922,0.002189662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01007034,"threshold_uncertainty_score":0.03368866,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03378009687224769,"score_gpt":0.3344156060484884,"score_spread":0.3006355091762407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}