{"id":"W4388591602","doi":"10.1016/j.bbapap.2023.140973","title":"Paradoxical effects on ice nucleation are intrinsic to a small winter flounder antifreeze protein","year":2023,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Dalhousie Medical Research Foundation","keywords":"Nucleation; Antifreeze protein; Ice nucleus; Chemistry; Crystallography; Winter flounder; Circular dichroism; Biophysics; Random hexamer; Biochemistry; Biology; Organic chemistry; Flounder","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001647725,0.0002572847,0.0002558029,0.0001160712,0.000115021,0.0002668425,0.0001747993,0.0002464417,0.0005339814],"category_scores_gemma":[0.0002627549,0.0001390912,0.0002193743,0.00007053817,0.0002750973,0.000207149,0.0002395827,0.0004952418,0.0001401108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001995041,"about_ca_system_score_gemma":0.00007452545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004016162,"about_ca_topic_score_gemma":0.0004739001,"domain_scores_codex":[0.9998038,0.00003037885,0.00001269781,0.00004598322,0.0000794006,0.00002770118],"domain_scores_gemma":[0.9997588,0.00008726205,0.00006559079,0.00002607541,0.00003246954,0.00002994337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003405965,0.000005930354,0.0002084094,0.00001920303,0.000002369493,0.00002085449,0.000009016153,0.0000156721,0.9993045,0.00001538463,0.000007039635,0.0003575024],"study_design_scores_gemma":[0.000002579965,0.000113848,0.007415336,0.000003431286,0.000005078061,0.0001262422,0.00001481735,0.0003799228,0.9914644,0.00002459953,0.0004473965,0.000002260817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965557,0.0009521436,0.001570546,0.00004325156,0.00001448721,0.00001222838,0.0001006088,0.00002750073,0.0007236125],"genre_scores_gemma":[0.9967285,0.0004463341,0.001788841,0.00007488824,0.000009272786,0.00001396012,0.0002067876,0.00002612679,0.0007053449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005339814,"threshold_uncertainty_score":0.001786292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01916313887118709,"score_gpt":0.2298667285155936,"score_spread":0.2107035896444065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}