{"id":"W4388596739","doi":"10.1016/j.rpth.2023.101441","title":"PB1348 Thrombopoietin Receptor Agonist and Rituximab Combination Therapy in Patients with Refractory Primary Immune Thrombocytopenia. A Single-Center Study","year":2023,"lang":"en","type":"article","venue":"Research and Practice in Thrombosis and Haemostasis","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Immune thrombocytopenia; Thrombopoietin receptor; Rituximab; Thrombopoietin; Refractory (planetary science); Romiplostim; Medicine; Agonist; Eltrombopag; Single Center; Immunology; Receptor; Antibody; Internal medicine; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009693441,0.0003576724,0.0009438885,0.0006343467,0.0005907718,0.0008096907,0.0005201138,0.0006565912,0.001978165],"category_scores_gemma":[0.001858878,0.0005287814,0.0008359059,0.001209129,0.0003305404,0.0004627979,0.0004064011,0.0006959033,0.000359655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001382016,"about_ca_system_score_gemma":0.001481499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01230098,"about_ca_topic_score_gemma":0.01629614,"domain_scores_codex":[0.9990351,0.0002881574,0.0001099593,0.0002067288,0.000223933,0.0001361449],"domain_scores_gemma":[0.9983902,0.0003027739,0.0006902478,0.00007839472,0.0001591651,0.0003792395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.001985343,0.0007444117,0.9924313,0.0001166518,0.0003118703,0.0006548674,0.0001843465,0.00005314229,0.000358546,0.00001590808,0.0002769267,0.002866634],"study_design_scores_gemma":[0.0007840866,0.002841955,0.9933758,0.00003968679,0.000328539,0.001364022,0.000344953,0.000294316,0.00006614261,0.00001459901,0.0005339049,0.00001196047],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983493,0.0007688163,0.00003562658,0.00004960858,0.000009085864,0.00007538802,0.0002046907,0.00000295131,0.0005045755],"genre_scores_gemma":[0.9990342,0.0002678499,0.00007661854,0.0001203708,0.000049239,0.00004500045,0.0002651028,0.000001676299,0.000140075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01230098,"threshold_uncertainty_score":0.02445877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1181000209806568,"score_gpt":0.393933045340223,"score_spread":0.2758330243595662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}