{"id":"W4388597530","doi":"10.1016/j.rpth.2023.101232","title":"PB0693 Efficacy and Safety of Eptacog Beta (Recombinant Activated FVII) in Patients with Hemophilia A or B with Inhibitors According to Time to Initial Infusion: A Post-Hoc Analysis from PERSEPT-1","year":2023,"lang":"en","type":"article","venue":"Research and Practice in Thrombosis and Haemostasis","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Recombinant DNA; Medicine; Post-hoc analysis; Pharmacology; Internal medicine; Chemistry; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002826033,0.0009310406,0.002695571,0.0003992361,0.0003023977,0.000995883,0.0006669657,0.000822174,0.00589311],"category_scores_gemma":[0.003597285,0.0004097961,0.00426816,0.0004472986,0.0007597159,0.001259766,0.00062295,0.002281072,0.0005676316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006038976,"about_ca_system_score_gemma":0.0008583381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001021089,"about_ca_topic_score_gemma":0.001534523,"domain_scores_codex":[0.9973927,0.001418748,0.0001444258,0.0004280559,0.0001994234,0.00041666],"domain_scores_gemma":[0.9968262,0.00197524,0.0003685157,0.0002485143,0.0001335408,0.0004480337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9476473,0.002191971,0.02254811,0.0002523521,0.007169234,0.00009922707,0.0001298607,0.00098895,0.002292412,0.0001291645,0.0009126536,0.01563881],"study_design_scores_gemma":[0.2080719,0.3693528,0.3841342,0.0001346693,0.01915574,0.0003696489,0.0006680543,0.009313884,0.004691544,0.0007647908,0.003129267,0.000213478],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977733,0.0006877433,0.0001685975,0.00009470287,0.00006906839,0.00007599834,0.0004447891,0.00001549977,0.0006701825],"genre_scores_gemma":[0.9972649,0.0003153084,0.0002217112,0.0001018409,0.00009072477,0.0001270779,0.0007438487,0.00001194065,0.001122696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00589311,"threshold_uncertainty_score":0.01971442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08241656726542833,"score_gpt":0.4082112566248118,"score_spread":0.3257946893593835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}