{"id":"W4388625848","doi":"10.25251/skin.7.supp.294","title":"Integrated Safety Analysis of Ritlecitinib in Adolescent Patients with Alopecia Areata from the Randomized, Placebo-Controlled ALLEGRO Phase 2b/3 and Ongoing Open-Label Phase 3 ALLEGRO-LT Studies","year":2023,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Hair Growth and Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Probity Medical Research","funders":"Pfizer","keywords":"Alopecia areata; Placebo; Phase (matter); Medicine; Open label; Dermatology; Randomized controlled trial; Psychology; Internal medicine; Alternative medicine; Physics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00295446,0.0005018918,0.001487323,0.0003504473,0.0002488536,0.0009014292,0.0005077283,0.0007401772,0.003707797],"category_scores_gemma":[0.002211585,0.0002383219,0.00224341,0.0003320229,0.0004250495,0.0007173172,0.0002412484,0.001960095,0.0004234827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008258413,"about_ca_system_score_gemma":0.001230143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005264452,"about_ca_topic_score_gemma":0.001838444,"domain_scores_codex":[0.9989453,0.0005914554,0.00006162579,0.0001315528,0.0001548724,0.0001151203],"domain_scores_gemma":[0.9985594,0.000465346,0.0004592084,0.0001275006,0.0001535042,0.0002349367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6732416,0.006176311,0.0137752,0.002335144,0.007541464,0.0001514101,0.0002039031,0.00286246,0.01541673,0.0005534015,0.004841545,0.2729008],"study_design_scores_gemma":[0.6456182,0.2384073,0.08119833,0.0003749128,0.009023777,0.0006764687,0.0001328244,0.002621526,0.005428689,0.0006769389,0.01574564,0.00009533139],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9746249,0.01564674,0.001383645,0.0007553575,0.0001569398,0.001470361,0.00276099,0.0001484517,0.003052667],"genre_scores_gemma":[0.9891592,0.003988043,0.001355119,0.0008856981,0.000167925,0.0008094389,0.002504246,0.00003095851,0.001099388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003707797,"threshold_uncertainty_score":0.01562482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0338854993569062,"score_gpt":0.3409284818206344,"score_spread":0.3070429824637282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}