{"id":"W4388626033","doi":"10.25251/skin.7.supp.286","title":"Spesolimab for Hidradenitis Suppurativa: A Proof-of-Concept Study","year":2023,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Hidradenitis Suppurativa and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"SKiN Health","funders":"","keywords":"Hidradenitis suppurativa; Medicine; Placebo; Internal medicine; Dosing; Intertriginous; Adverse effect; Gastroenterology; Adalimumab; Surgery; Pathology; Tumor necrosis factor alpha","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004226682,0.001548741,0.001362264,0.0003904138,0.0002515218,0.001221551,0.000874746,0.001469483,0.005812435],"category_scores_gemma":[0.001253538,0.0003641909,0.00193763,0.0002835655,0.0005831784,0.0007455194,0.0004010413,0.002438138,0.001314753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005180499,"about_ca_system_score_gemma":0.001645954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001568641,"about_ca_topic_score_gemma":0.0004252089,"domain_scores_codex":[0.9992254,0.0003717762,0.00004774132,0.00008726525,0.0001511381,0.0001165938],"domain_scores_gemma":[0.9990496,0.0002372985,0.0002333272,0.00006712976,0.0001356448,0.0002770444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1868001,0.07053368,0.003094547,0.0229741,0.004346145,0.001909856,0.0005940634,0.003450399,0.3326042,0.001962432,0.02565305,0.3460774],"study_design_scores_gemma":[0.3017367,0.5812956,0.007961035,0.001149905,0.00246888,0.003017812,0.0001432364,0.001749334,0.03670371,0.0007418978,0.06295233,0.00007946201],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.852337,0.09258215,0.01451114,0.004718138,0.001930424,0.01686107,0.006091322,0.0005402801,0.01042844],"genre_scores_gemma":[0.9240038,0.03779347,0.01315338,0.004375774,0.001124184,0.008413979,0.004852719,0.00005695776,0.006225727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005812435,"threshold_uncertainty_score":0.02235311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03057522950790823,"score_gpt":0.3238723228457288,"score_spread":0.2932970933378206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}