{"id":"W4388626054","doi":"10.25251/skin.7.supp.291","title":"Integrated Safety Analysis of Ritlecitinib for the Treatment of Alopecia Areata (AA) From the Phase 2 and Phase 3 ALLEGRO Clinical Trial Program","year":2023,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Hair Growth and Disorders","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research","funders":"Pfizer","keywords":"Alopecia areata; Phase (matter); Dermatology; Medicine; Chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001892457,0.0002138189,0.001238314,0.0002028649,0.0001234082,0.000007783135,0.0003008806,0.0001015335,0.0003313625],"category_scores_gemma":[0.001953745,0.00007728092,0.0005333757,0.0009542325,0.0007399565,0.00002446798,0.00002100968,0.0002604813,0.000001007825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003439566,"about_ca_system_score_gemma":0.0002225646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002355442,"about_ca_topic_score_gemma":0.0002915101,"domain_scores_codex":[0.9971915,0.0003154664,0.001527532,0.0001633017,0.0005644382,0.0002377183],"domain_scores_gemma":[0.9913949,0.006905908,0.000712804,0.0004786564,0.0003271211,0.0001805551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.1996503,0.004082253,0.0009227951,0.0000301033,0.01056702,0.0002569529,0.005778976,0.00005050141,0.0004564434,0.00003213216,0.01589427,0.7622783],"study_design_scores_gemma":[0.3373157,0.09068259,0.001990881,0.0005295298,0.04830418,0.0006891079,0.02197047,0.01516143,0.0005040145,0.0004594802,0.4821549,0.0002376469],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825345,0.004352961,0.000769306,0.009232134,0.0004829945,0.001910394,0.0004469641,0.00001869814,0.0002520084],"genre_scores_gemma":[0.9830878,0.01446661,0.0002262489,0.0003765044,0.001276814,0.00002173877,0.0003064568,0.00002541228,0.0002124359],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7620407,"threshold_uncertainty_score":0.3628187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08132641213904793,"score_gpt":0.4348392751947991,"score_spread":0.3535128630557511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}