{"id":"W4388626054","doi":"10.25251/skin.7.supp.291","title":"Integrated Safety Analysis of Ritlecitinib for the Treatment of Alopecia Areata (AA) From the Phase 2 and Phase 3 ALLEGRO Clinical Trial Program","year":2023,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Hair Growth and Disorders","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research","funders":"Pfizer","keywords":"Alopecia areata; Phase (matter); Dermatology; Medicine; Chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009266319,0.0012139,0.002267443,0.00121718,0.0006100045,0.002065133,0.0008272818,0.001478273,0.01003502],"category_scores_gemma":[0.005173154,0.0005392226,0.004792573,0.0009758482,0.0004147249,0.001059116,0.001000691,0.001910503,0.001015913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001082754,"about_ca_system_score_gemma":0.002934998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006332808,"about_ca_topic_score_gemma":0.002472422,"domain_scores_codex":[0.9957588,0.002477063,0.0002847296,0.0004088829,0.0007614049,0.0003090265],"domain_scores_gemma":[0.9968631,0.0008776273,0.001076449,0.0002346869,0.0005262467,0.0004220201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.666626,0.007244369,0.0211509,0.01127105,0.03370376,0.0004953414,0.0004108375,0.003745575,0.02332114,0.001146247,0.02759235,0.2032924],"study_design_scores_gemma":[0.5799936,0.1661908,0.110154,0.00233352,0.04501339,0.001304562,0.0002517371,0.002852448,0.00860035,0.001862226,0.08123219,0.0002111563],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8061053,0.04982499,0.007046453,0.003566132,0.0004515313,0.04594265,0.06447299,0.000680619,0.02190931],"genre_scores_gemma":[0.8807061,0.01644962,0.009428374,0.004992759,0.0006158321,0.03078312,0.04832015,0.000206536,0.008497413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01003502,"threshold_uncertainty_score":0.04900557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08132641213904793,"score_gpt":0.4348392751947991,"score_spread":0.3535128630557511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}