{"id":"W4388626087","doi":"10.25251/skin.7.supp.256","title":"A Phase 3b Study Evaluating Safety and Efficacy of Risankizumab in Adult Patients with Moderate-to-Severe Plaque Psoriasis with Palmoplantar (Non-Pustular) Involvement","year":2023,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovaderm (Canada)","funders":"","keywords":"Medicine; Psoriasis Area and Severity Index; Randomized controlled trial; Placebo; Clinical endpoint; Internal medicine; Gastroenterology; Psoriasis; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002171268,0.000770317,0.001329932,0.000186725,0.0003030491,0.0005097638,0.0005248772,0.000741542,0.005087553],"category_scores_gemma":[0.0009731834,0.0003995558,0.001147627,0.0002446481,0.0004714473,0.0004594762,0.0002461176,0.002057314,0.0009445812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004802333,"about_ca_system_score_gemma":0.001279255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005235256,"about_ca_topic_score_gemma":0.001417305,"domain_scores_codex":[0.9994771,0.0002954193,0.0000302589,0.00006618625,0.00006363819,0.0000673973],"domain_scores_gemma":[0.9993206,0.0001344289,0.0001638906,0.00005410078,0.00005936881,0.0002675718],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8781276,0.0318559,0.008915035,0.0007496623,0.00114767,0.000141595,0.0001634291,0.0006778619,0.02278631,0.0001398237,0.002985074,0.05230993],"study_design_scores_gemma":[0.7340205,0.2426145,0.01870494,0.00003680601,0.0004466929,0.000186715,0.00002602873,0.00042402,0.00162811,0.000105419,0.001790386,0.00001590898],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987716,0.00300418,0.0007052679,0.0004885753,0.0001017393,0.004107016,0.001751972,0.00008086541,0.002044372],"genre_scores_gemma":[0.9891911,0.001326084,0.001825304,0.0008903809,0.0001728943,0.003313891,0.001812246,0.00001869609,0.001449636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005087553,"threshold_uncertainty_score":0.01701957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03396525115363107,"score_gpt":0.3609531808656619,"score_spread":0.3269879297120308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}