{"id":"W4388627418","doi":"10.1038/s41598-023-47073-0","title":"The role of MOTS-c-mediated antioxidant defense in aerobic exercise alleviating diabetic myocardial injury","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"GDF15 and Related Biomarkers","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Natural Science Foundation of China","keywords":"AMPK; Antioxidant; Aerobic exercise; Medicine; Superoxide dismutase; Internal medicine; Lipid peroxidation; Diabetes mellitus; Diabetic cardiomyopathy; Endocrinology; Cardiac function curve; Oxidative stress; Streptozotocin; Glutathione; Pharmacology; Protein kinase A; Chemistry; Biochemistry; Kinase; Heart failure; Cardiomyopathy; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001412437,0.0003708475,0.0002689468,0.0002855639,0.0001719794,0.0001734622,0.0001693426,0.0002842105,0.0007845029],"category_scores_gemma":[0.0000792066,0.00007650931,0.0003595553,0.0001494489,0.0001996675,0.0002165916,0.0002217857,0.0003756983,0.00007775082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000129674,"about_ca_system_score_gemma":0.0002143955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003650773,"about_ca_topic_score_gemma":0.0007355231,"domain_scores_codex":[0.9999512,0.000009113392,0.000005159434,0.000008689295,0.000009653809,0.00001615716],"domain_scores_gemma":[0.9999477,0.000003973503,0.00001521158,0.000003207216,0.000009882237,0.00001997653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001771165,0.0002990889,0.001328185,0.0005242581,0.00006521561,0.0001459456,0.00003390173,0.0002709353,0.980319,0.000221343,0.0001472767,0.01487371],"study_design_scores_gemma":[0.0003384456,0.00590259,0.04653154,0.0001383253,0.0002415638,0.0006965405,0.0001649466,0.002791662,0.9349076,0.0003456369,0.007905012,0.00003614447],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854725,0.01107223,0.001640381,0.0002519676,0.00006955181,0.00005723871,0.0002514932,0.00004307846,0.001141532],"genre_scores_gemma":[0.9924952,0.004295934,0.001578843,0.0001553958,0.0000257654,0.00004054036,0.0003098228,0.000005250248,0.001093238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007845029,"threshold_uncertainty_score":0.002624452,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006820391801440188,"score_gpt":0.2346128241956321,"score_spread":0.2277924323941919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}