{"id":"W4388627693","doi":"10.25251/skin.7.supp.281","title":"Rapid and Early Onset of Itch Relief with Tapinarof Cream 1% Once Daily in Two Pivotal Phase 3 Trials in Adults and Children Down to Two Years of Age with Atopic Dermatitis","year":2023,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Innovaderm (Canada)","funders":"","keywords":"Atopic dermatitis; Medicine; Pediatrics; Dermatology; Age of onset; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002086833,0.001261681,0.002804129,0.0003287657,0.0003522537,0.001030169,0.0006289968,0.001172378,0.004561101],"category_scores_gemma":[0.001434303,0.0004708491,0.002253266,0.0003234488,0.0007459,0.0007939682,0.0003019158,0.003028811,0.0005966829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005888584,"about_ca_system_score_gemma":0.0009046484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001038828,"about_ca_topic_score_gemma":0.004177808,"domain_scores_codex":[0.999511,0.0002012167,0.00003026183,0.00007666936,0.0000410824,0.0001397262],"domain_scores_gemma":[0.9992509,0.0002738489,0.0001030969,0.00004637053,0.00005291274,0.0002728809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8030179,0.02065296,0.004555746,0.00349117,0.002261696,0.0005879765,0.0007570763,0.001153237,0.0308183,0.0005306429,0.005038915,0.1271344],"study_design_scores_gemma":[0.7453317,0.2341072,0.01317772,0.000179704,0.0007618041,0.000420935,0.0001500056,0.0003261774,0.001675511,0.0002259716,0.003604463,0.00003873986],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9801027,0.01285435,0.0006638732,0.0007987033,0.0003024401,0.002073986,0.001162051,0.00009465765,0.001947157],"genre_scores_gemma":[0.9856406,0.006858235,0.0015817,0.0009876,0.0001840362,0.001753667,0.00127069,0.0000327767,0.001690683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004561101,"threshold_uncertainty_score":0.01525837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01153428356414079,"score_gpt":0.3018642160157428,"score_spread":0.290329932451602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}