{"id":"W4388630072","doi":"10.3390/ph16111600","title":"Docetaxel-Loaded Methoxy poly(ethylene glycol)-poly (L-lactic Acid) Nanoparticles for Breast Cancer: Synthesis, Characterization, Method Validation, and Cytotoxicity","year":2023,"lang":"en","type":"article","venue":"Pharmaceuticals","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Higher Education Commission Mauritius; Higher Education Commission, Pakistan; King Saud University","keywords":"Clonogenic assay; Cytotoxicity; Ethylene glycol; MTT assay; Chemistry; Docetaxel; MCF-7; In vitro; Cancer cell; Human breast; Medicine; Biochemistry; Cancer; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004992604,0.0004413461,0.0003285792,0.0002917053,0.0001888623,0.0003290586,0.0002546177,0.0003471058,0.0003789788],"category_scores_gemma":[0.0003833163,0.0002185748,0.0003062031,0.0002172238,0.0001710014,0.0002426205,0.0001644037,0.0003312167,0.0003623663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004602954,"about_ca_system_score_gemma":0.0003205063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009438989,"about_ca_topic_score_gemma":0.002018286,"domain_scores_codex":[0.9996098,0.00006280359,0.00004425017,0.00007524998,0.0001859292,0.00002208203],"domain_scores_gemma":[0.9998683,0.00002725568,0.000032936,0.00001348182,0.00004977165,0.000008255908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004775177,0.00003717784,0.0001764866,0.000196773,0.000007705914,0.00007762091,0.00003078802,0.0003854905,0.9922662,0.00007846447,0.00007252114,0.006623017],"study_design_scores_gemma":[0.000005830977,0.0001821091,0.0008126572,0.00001114198,0.00001897602,0.000228543,0.00001262206,0.002320358,0.9936168,0.00002242183,0.002757372,0.00001117016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8630103,0.01734321,0.1120613,0.0003346852,0.0001534897,0.0006540875,0.0007413743,0.0003859477,0.005315541],"genre_scores_gemma":[0.9008979,0.007787736,0.08319964,0.0001523017,0.00003396496,0.0006205663,0.0006697908,0.00008691986,0.006551277],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009438989,"threshold_uncertainty_score":0.003339708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0509215988111227,"score_gpt":0.3623088589149903,"score_spread":0.3113872601038676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}