{"id":"W4388631056","doi":"10.1186/s11689-023-09508-7","title":"A mouse model of ATRX deficiency with cognitive deficits and autistic traits","year":2023,"lang":"en","type":"article","venue":"Journal of Neurodevelopmental Disorders","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Western University","funders":"Robarts Research Institute","keywords":"ATRX; Forebrain; Neuroscience; Autism; Psychology; Biology; Developmental psychology; Genetics; Gene; Mutation; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004099478,0.002325111,0.0006316105,0.00336085,0.0008832596,0.0005133851,0.001000327,0.002275409,0.00679552],"category_scores_gemma":[0.000269022,0.0005753044,0.0007450816,0.0007723855,0.001072069,0.000600387,0.0008281119,0.00227568,0.001850429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008133771,"about_ca_system_score_gemma":0.0006301689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001461107,"about_ca_topic_score_gemma":0.002624565,"domain_scores_codex":[0.9994642,0.00005073816,0.00008424087,0.0001719184,0.0001450478,0.00008386149],"domain_scores_gemma":[0.9993353,0.00009464349,0.0002633839,0.00006575586,0.00006182319,0.0001790161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001019649,0.0007401514,0.001295785,0.0001816563,0.00007711576,0.003304064,0.0002127008,0.0002711714,0.9866748,0.000905282,0.0008244443,0.004493141],"study_design_scores_gemma":[0.001077727,0.006715165,0.03920041,0.000371016,0.0006521505,0.0371896,0.0006535785,0.006092466,0.8684456,0.002284158,0.03717101,0.0001471858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9716319,0.002059802,0.009517674,0.001203016,0.0002752653,0.0004699802,0.005181825,0.001571804,0.008088734],"genre_scores_gemma":[0.9256514,0.002702223,0.02505105,0.0008514919,0.0000895517,0.001629863,0.00670997,0.0004615124,0.03685274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00679552,"threshold_uncertainty_score":0.02273327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01229390984941771,"score_gpt":0.2264099674737409,"score_spread":0.2141160576243232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}