{"id":"W4388645602","doi":"10.1101/2023.11.11.566669","title":"Intestinal cDC1s provide IL-12 dependent and independent functions required for CD4 <sup>+</sup> T cell-mediated resistance to <i>Cryptosporidium</i>","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Parasitic Infections and Diagnostics","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Biology; Effector; Priming (agriculture); Cell biology; T cell; Immune system; Antigen-presenting cell; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001201423,0.0004612707,0.0002174482,0.0002590718,0.0002172089,0.0003789241,0.0002199095,0.0002227474,0.002601663],"category_scores_gemma":[0.0001004115,0.0001888286,0.0002092529,0.00008248851,0.0002032976,0.0001349516,0.0001919599,0.0007810717,0.0008315817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002825705,"about_ca_system_score_gemma":0.0002197689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004946596,"about_ca_topic_score_gemma":0.0008714172,"domain_scores_codex":[0.9998454,0.00002896117,0.00001499976,0.00002586632,0.00002893342,0.00005576606],"domain_scores_gemma":[0.999786,0.00002794277,0.00005223324,0.00003169956,0.00002745614,0.00007477124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002324606,0.00004854086,0.0002624074,0.0000339496,0.00000230551,0.00004814556,0.0000128122,0.00006362923,0.9984362,0.0000806965,0.0000720294,0.0007070259],"study_design_scores_gemma":[0.0000310416,0.0002552398,0.004535913,0.000009420157,0.000008361522,0.0001462003,0.00004006964,0.0009745936,0.9916956,0.0000277985,0.002272341,0.000003319931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954838,0.0005151089,0.001186981,0.00009574311,0.00003373044,0.00003424557,0.0005784951,0.0001274233,0.00194455],"genre_scores_gemma":[0.9937914,0.0001695064,0.001198862,0.00003479557,0.0000110098,0.00004321723,0.0008934573,0.00003955109,0.003818202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002601663,"threshold_uncertainty_score":0.008703411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01654884968747556,"score_gpt":0.2262932139763117,"score_spread":0.2097443642888362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}