{"id":"W4388646345","doi":"10.1002/jgm.3627","title":"Enhancement of adeno‐associated virus serotype 6 transduction into T cells with cell‐penetrating peptides","year":2023,"lang":"en","type":"article","venue":"The Journal of Gene Medicine","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de Recherche du Québec - Santé; Canada Research Chairs; Faculty of Engineering, McGill University","keywords":"Transduction (biophysics); Jurkat cells; Biology; Viral vector; Transgene; Cell culture; Cell biology; Gene delivery; Multiplicity of infection; Potato virus X; Molecular biology; Virology; T cell; Virus; Transfection; Immune system; Immunology; Gene; Biochemistry; Genetics; Plant virus; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001692451,0.0001241871,0.0002228391,0.0001028181,0.00008443751,0.000004012359,0.0002755431,0.00006105653,0.00007992411],"category_scores_gemma":[0.00004878613,0.00007260374,0.00005277582,0.0003207088,0.000161061,0.000004528071,0.00002252091,0.0001732053,0.000005126844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002759345,"about_ca_system_score_gemma":0.0001378554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004887701,"about_ca_topic_score_gemma":0.0001676734,"domain_scores_codex":[0.9985949,0.0002132847,0.0003991189,0.0001079713,0.0004819919,0.0002027546],"domain_scores_gemma":[0.999027,0.00004227291,0.0003460805,0.0002170514,0.0002937324,0.00007391758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002102042,0.00005476125,0.0001055523,0.00002693883,0.0001469968,0.000005596213,0.001023721,0.001155476,0.9928499,2.181479e-7,0.001381023,0.001147723],"study_design_scores_gemma":[0.001236524,0.0113272,0.0003024894,0.00007805997,0.00006933248,0.00001646123,0.0008441407,0.00004377178,0.9857194,0.00002162087,0.0002676836,0.00007335439],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963138,0.001897967,0.000693894,0.0007069705,0.0001261576,0.0001472277,0.000002724662,0.000004350894,0.0001069462],"genre_scores_gemma":[0.9961327,0.00276086,0.000163222,0.0001003802,0.0003624624,0.000002641471,0.00001810005,0.00002236436,0.0004373239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01127244,"threshold_uncertainty_score":0.2960694,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01779368960079492,"score_gpt":0.2904554496241775,"score_spread":0.2726617600233825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}