{"id":"W4388648413","doi":"10.1101/2023.11.08.566332","title":"General anaesthesia reduces the uniqueness of brain connectivity across individuals and across species","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Mila - Quebec Artificial Intelligence Institute; McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Unconsciousness; Propofol; Macaque; General anaesthesia; Human brain; Optimal distinctiveness theory; Neuroscience; Psychology; Anesthesia; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004432641,0.000207769,0.0002394105,0.0003980557,0.0002885445,0.0005659097,0.0001778272,0.0002543969,0.001716697],"category_scores_gemma":[0.002735371,0.0001671622,0.0002348244,0.0002229533,0.0007901072,0.000613182,0.0007764946,0.0004270754,0.0001198973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000195249,"about_ca_system_score_gemma":0.0002123686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009777583,"about_ca_topic_score_gemma":0.002380302,"domain_scores_codex":[0.9996794,0.00007299239,0.00002642135,0.0001237438,0.00006075563,0.00003658162],"domain_scores_gemma":[0.9990096,0.0003117996,0.0003611934,0.00017844,0.00006645508,0.00007247661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000695281,0.00004335229,0.06434699,0.0004036895,0.0005282004,0.0003837865,0.001495156,0.002146994,0.8846703,0.002387768,0.0004100911,0.04248849],"study_design_scores_gemma":[0.00001950641,0.0005552524,0.9269747,0.00005110566,0.0002661294,0.001418945,0.0007001116,0.00350792,0.05869964,0.004969072,0.002799505,0.00003816083],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909374,0.0004885143,0.006502253,0.0001549781,0.00001107658,0.00001265085,0.0002203814,0.00006132366,0.001611411],"genre_scores_gemma":[0.9975484,0.0001970446,0.001714095,0.0000522419,0.000008406229,0.00001639391,0.0001917126,0.00003861658,0.0002330548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001716697,"threshold_uncertainty_score":0.005742967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05300178608605784,"score_gpt":0.2853049994849537,"score_spread":0.2323032133988959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}