{"id":"W4388653149","doi":"10.1097/shk.0000000000002274","title":"SINGLE-CELL TRANSCRIPTOME ANALYSIS IN HEALTH AND DISEASE","year":2023,"lang":"en","type":"article","venue":"Shock","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Population Health Research Institute; McMaster University; Thrombosis and Atherosclerosis Research Institute; Hamilton Health Sciences; Hamilton General Hospital","funders":"National Institute of General Medical Sciences; National Institute on Aging","keywords":"Transcriptome; Computational biology; Single-cell analysis; Biology; Gene expression profiling; KEGG; Cell; Bioinformatics; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001278621,0.0004804788,0.0008542536,0.001513485,0.0004108583,0.001195667,0.0004685312,0.0006428761,0.002014373],"category_scores_gemma":[0.0007334484,0.0002161847,0.0007068278,0.001643314,0.0004825442,0.0006581493,0.001071927,0.0008085138,0.001100739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004385518,"about_ca_system_score_gemma":0.0006525344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006701691,"about_ca_topic_score_gemma":0.0009439875,"domain_scores_codex":[0.9995238,0.00009773609,0.00003763465,0.0001441051,0.0001403142,0.00005640892],"domain_scores_gemma":[0.9995369,0.0001290626,0.00007922625,0.00006206211,0.0001264184,0.00006636788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005938109,0.0000946628,0.02155479,0.00219408,0.0003811405,0.0008185983,0.0004746957,0.005139228,0.8178216,0.0041606,0.01039085,0.1363759],"study_design_scores_gemma":[0.00007118591,0.0006258989,0.204857,0.0008126699,0.000744173,0.0039451,0.00101147,0.06094812,0.5705611,0.02856833,0.1275522,0.0003027417],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3512819,0.05051146,0.5484936,0.002683734,0.001066795,0.0003640302,0.02959979,0.007211812,0.008786912],"genre_scores_gemma":[0.7402021,0.02330682,0.2074485,0.001729091,0.0004307737,0.0006891317,0.01983734,0.001001198,0.005355068],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002014373,"threshold_uncertainty_score":0.006762087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01822049911996216,"score_gpt":0.2469334540352703,"score_spread":0.2287129549153081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}