{"id":"W4388655672","doi":"10.1128/spectrum.03116-23","title":"The diagnostic accuracy of the GeneXpert ESBL- <i>ampC</i> prototype assay for rapid PCR-based detection of extended-spectrum beta-lactamase genes directly from urine","year":2023,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"GeneXpert MTB/RIF; Urine; Microbiology; Beta-lactamase; Cephalosporin; Biology; Antibiotics; Medicine; Virology; Gene; Tuberculosis; Internal medicine; Escherichia coli; Genetics; Sputum; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004867645,0.0002928299,0.0003658773,0.00005714069,0.0002536545,0.00002018203,0.000640653,0.0002978759,0.00002841988],"category_scores_gemma":[0.0007723957,0.000190192,0.0003210265,0.0002494846,0.000522593,0.000005686969,0.000192338,0.0001414909,0.000009969172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003459247,"about_ca_system_score_gemma":0.0001603571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001004041,"about_ca_topic_score_gemma":0.0007889789,"domain_scores_codex":[0.9980277,0.0003069282,0.000540803,0.000541475,0.00008042563,0.0005026036],"domain_scores_gemma":[0.9976738,0.0007987366,0.000458788,0.0009375064,0.00008399821,0.00004718352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006412195,0.00008081298,0.004588006,0.00003704458,0.0001660488,0.00000150482,0.00001772944,0.00002647429,0.9919143,0.00005182321,0.0006369776,0.001838043],"study_design_scores_gemma":[0.0007243805,0.0005103824,0.01695437,0.00003042361,0.00006062877,0.000007758651,0.00003424798,0.00004805927,0.940278,0.0002494695,0.04089752,0.000204756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919648,0.002312112,0.001405072,0.001412503,0.0007571965,0.001546446,0.0005069483,0.00003902112,0.00005587744],"genre_scores_gemma":[0.9978325,0.0007552303,0.0002449067,0.0001291135,0.0002655343,0.0001559096,0.0003585385,0.00005106567,0.0002071484],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05163631,"threshold_uncertainty_score":0.7755806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009278074660947214,"score_gpt":0.2380284429069438,"score_spread":0.2287503682459966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}