{"id":"W4388655698","doi":"10.1128/spectrum.01613-23","title":"Honduras HIV cohort: HLA class I and CCR5-Δ32 profiles and their associations with HIV disease outcome","year":2023,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Consejo Nacional de Ciencia y Tecnología; Government of Canada","keywords":"Human immunodeficiency virus (HIV); Human leukocyte antigen; Cohort; Disease; Medicine; Demography; Cohort study; Immunology; Virology; Internal medicine; Sociology; Antigen","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002873997,0.0001794824,0.0001651262,0.0003533468,0.0003885555,0.0004655553,0.0002387187,0.0001904629,0.001158184],"category_scores_gemma":[0.000496152,0.0001432562,0.0001643322,0.0005560745,0.0001433475,0.0001963818,0.0002998358,0.0002856679,0.0001131015],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002285208,"about_ca_system_score_gemma":0.0001544713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03279456,"about_ca_topic_score_gemma":0.03141348,"domain_scores_codex":[0.9998837,0.00002431569,0.000009403338,0.00003444851,0.00001789512,0.00003026001],"domain_scores_gemma":[0.9997084,0.00003521583,0.00009113356,0.00004617596,0.0000365206,0.00008264572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009262197,0.000008661699,0.9988328,0.000002306818,0.00002089613,0.00004809213,0.00004991223,0.00002209761,0.0003104366,0.00000671279,0.0000401693,0.0005654012],"study_design_scores_gemma":[0.000003901585,0.0000251541,0.9995508,0.00000200456,0.00001107655,0.00008192726,0.0001248838,0.00008572355,0.00002631041,0.0000055747,0.00008137317,0.000001206863],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994962,0.00006400936,0.00001936222,0.000007085214,0.000001175662,0.000002361874,0.0002373268,0.00000111409,0.0001713193],"genre_scores_gemma":[0.9996941,0.00002453316,0.00002184739,0.00000489244,0.000001674784,0.000001787752,0.0001744578,5.567388e-7,0.00007619848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03279456,"threshold_uncertainty_score":0.06520736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01262741673040807,"score_gpt":0.2421502994005853,"score_spread":0.2295228826701773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}