{"id":"W4388666218","doi":"10.1016/j.clml.2023.11.001","title":"Teclistamab Improves Patient-Reported Symptoms and Health-Related Quality of Life in Relapsed or Refractory Multiple Myeloma: Results From the Phase II MajesTEC-1 Study","year":2023,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; University of Calgary","funders":"","keywords":"Medicine; Quality of life (healthcare); Post-hoc analysis; Physical therapy; Internal medicine; Refractory (planetary science); Health related quality of life; Clinical trial; Multiple myeloma; Minimal clinically important difference; Disease; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003177622,0.0006091685,0.001093727,0.0002339742,0.0001894526,0.0006157394,0.0004144988,0.0005092346,0.001198311],"category_scores_gemma":[0.001401351,0.0001931288,0.0009906226,0.0002669679,0.0002891032,0.0002941554,0.0002286159,0.001269926,0.0002395889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003972074,"about_ca_system_score_gemma":0.0005471465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004855733,"about_ca_topic_score_gemma":0.001368853,"domain_scores_codex":[0.9993746,0.0003410174,0.00004722687,0.00006125931,0.0001188802,0.00005707355],"domain_scores_gemma":[0.9990735,0.0002300275,0.0003632381,0.00007628652,0.00007707234,0.0001798395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3566167,0.02970813,0.09390173,0.002786166,0.008451236,0.0003716371,0.0003980251,0.005020396,0.06932684,0.0001529732,0.009220645,0.4240454],"study_design_scores_gemma":[0.1770868,0.3748015,0.4211014,0.0002631801,0.003856389,0.001171004,0.000134805,0.003701988,0.01037756,0.0002107186,0.007206216,0.00008858467],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880736,0.009615636,0.0001863402,0.0003416064,0.00004703576,0.0002291412,0.0006580805,0.00007058137,0.0007780024],"genre_scores_gemma":[0.9938886,0.002647112,0.0004940546,0.0006136828,0.0000847812,0.0001981849,0.001386794,0.00001201311,0.0006746665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003177622,"threshold_uncertainty_score":0.01680511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1184171867158281,"score_gpt":0.4102881281390837,"score_spread":0.2918709414232555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}