{"id":"W4388674869","doi":"10.1038/s41598-023-49129-7","title":"Network dynamical stability analysis reveals key “mallostatic” natural variables that erode homeostasis and drive age-related decline of health","year":2023,"lang":"en","type":"preprint","venue":"Scientific Reports","topic":"Mental Health Research Topics","field":"Psychology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"National Institute on Aging; Natural Sciences and Engineering Research Council of Canada; National Institute for Health and Care Research; Government of the United Kingdom","keywords":"Key (lock); Homeostasis; Biology; Medicine; Gerontology; Ecology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001042571,0.0003671421,0.0003376427,0.0008469684,0.0002317021,0.0006466176,0.0003203545,0.0003011517,0.001270281],"category_scores_gemma":[0.00468256,0.0001611413,0.0005372685,0.0003808536,0.0004533588,0.0007890809,0.0004681986,0.0005175925,0.0001197279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006665054,"about_ca_system_score_gemma":0.0004353244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003539717,"about_ca_topic_score_gemma":0.00395602,"domain_scores_codex":[0.9997118,0.00008621399,0.00001248663,0.0001280297,0.00003396686,0.00002739991],"domain_scores_gemma":[0.9986376,0.0006576221,0.0003730598,0.0001268072,0.0001278714,0.00007698965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0005814573,0.0002200992,0.2542953,0.0003099545,0.000877324,0.0004801195,0.0006226653,0.5415297,0.05467483,0.06492157,0.003254296,0.07823277],"study_design_scores_gemma":[0.00001132824,0.00009359719,0.06752724,0.00001909928,0.00006326981,0.0001049197,0.00008832302,0.897979,0.002428348,0.03070796,0.0009452549,0.00003165873],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7753264,0.0003834681,0.2203703,0.0004665935,0.00003372883,0.00005009569,0.001283194,0.0002089021,0.001877226],"genre_scores_gemma":[0.9869485,0.0001376474,0.01183132,0.00003216821,0.0000118099,0.00004033294,0.0004859593,0.00001816516,0.0004940957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003539717,"threshold_uncertainty_score":0.007038236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1055658485844162,"score_gpt":0.409335545422627,"score_spread":0.3037696968382108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}