{"id":"W4388677903","doi":"10.1039/d3tb01490h","title":"Different drug loading methods and antibiotic structure modulate the efficacy of polydopamine nanoparticles as drug nanocarriers","year":2023,"lang":"en","type":"article","venue":"Journal of Materials Chemistry B","topic":"Polymer Surface Interaction Studies","field":"Materials Science","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Research, Innovation and Science; Canada Foundation for Innovation; Research Corporation for Science Advancement","keywords":"Nanocarriers; Drug; Materials science; Nanoparticle; Nanotechnology; Drug delivery; Pharmacology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002144724,0.0002449838,0.0001415966,0.0001661756,0.00009547426,0.0002316007,0.0001698867,0.0002155296,0.0005687596],"category_scores_gemma":[0.0003409489,0.0001294686,0.0001424446,0.0001367564,0.0002029124,0.0002772372,0.0001183035,0.0002407425,0.0001607624],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001854297,"about_ca_system_score_gemma":0.0000990263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000472676,"about_ca_topic_score_gemma":0.0007817858,"domain_scores_codex":[0.9998765,0.00001844148,0.00001498834,0.00003220904,0.00003414011,0.00002371906],"domain_scores_gemma":[0.9998288,0.0000814413,0.00004477839,0.00001151731,0.00002195243,0.0000114465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005863122,0.0000186128,0.0001027294,0.0000381293,0.000003439916,0.00001231035,0.00001841673,0.0002493321,0.9978114,0.00004908512,0.0000206733,0.001617292],"study_design_scores_gemma":[0.000002720878,0.00006525756,0.0004439679,0.000002005335,0.000005236907,0.000007879409,0.0000068708,0.001632476,0.9976171,0.00001138874,0.0002020699,0.000003004488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960935,0.0009418651,0.002041155,0.00003009446,0.00001309137,0.000015263,0.0000673894,0.00004046729,0.0007572716],"genre_scores_gemma":[0.9957823,0.0006742359,0.002872888,0.00002122201,0.000003905081,0.0000207421,0.00004605141,0.00001812738,0.0005604836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005687596,"threshold_uncertainty_score":0.00190264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01360337934837413,"score_gpt":0.3090831199709858,"score_spread":0.2954797406226116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}