{"id":"W4388688064","doi":"10.1182/bloodadvances.2023010716","title":"New and emerging therapies for women, girls, and people with the potential to menstruate with VWD","year":2023,"lang":"en","type":"article","venue":"Blood Advances","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"CSL Behring","keywords":"Desmopressin; Von Willebrand factor; Medicine; Von Willebrand disease; Menstrual bleeding; Clinical trial; Intensive care medicine; Pediatrics; Gynecology; Immunology; Internal medicine; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003910895,0.0001011342,0.0001654673,0.00003652812,0.0001255411,0.00002384445,0.00002528476,0.00001210754,0.00000647518],"category_scores_gemma":[0.000004416658,0.00004986372,0.00001002347,0.0001469786,0.00002816378,0.00007351846,0.00001503838,0.00002843449,0.00000158636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003437901,"about_ca_system_score_gemma":0.00002189123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002416627,"about_ca_topic_score_gemma":0.0002481201,"domain_scores_codex":[0.999478,0.000004761358,0.00005262838,0.0001698453,0.00009855031,0.0001962125],"domain_scores_gemma":[0.9997668,0.00002864294,0.00002514248,0.0000787293,0.00001882776,0.00008189904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.00609404,0.0004291443,0.2767754,0.0006689844,0.003485403,0.0007097275,0.03306653,0.000328826,0.006982346,0.0006444813,0.003246524,0.6675686],"study_design_scores_gemma":[0.05465318,0.01617493,0.6612951,0.000588486,0.001902685,0.001466849,0.05654374,0.0003925426,0.005590713,0.006835921,0.1932668,0.001289106],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920188,0.002419777,0.000230748,0.004730365,0.00002126811,0.0004210714,0.000008385436,0.00004135235,0.0001082718],"genre_scores_gemma":[0.9949472,0.0008181671,0.002208065,0.0002084409,0.00004120449,0.00009794882,0.000006954062,0.00001588472,0.001656169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6662794,"threshold_uncertainty_score":0.2033383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00500709711098454,"score_gpt":0.2388379164809179,"score_spread":0.2338308193699333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}