{"id":"W4388705003","doi":"10.1007/s12192-023-01381-6","title":"Heat shock protein 27 in the pathogenesis of COVID-19 and non-COVID acute respiratory distress syndrome","year":2023,"lang":"en","type":"article","venue":"Cell Stress and Chaperones","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"Alberta Health Services","keywords":"ARDS; Medicine; Mechanical ventilation; Intensive care unit; Systemic inflammation; Shock (circulatory); Intensive care; Respiratory failure; Hsp27; Diffuse alveolar damage; Immunology; Inflammation; Internal medicine; Hsp70; Lung; Heat shock protein; Intensive care medicine; Acute respiratory distress; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000345175,0.0001741389,0.0002073305,0.00009120776,0.0001387708,0.00003434098,0.0002596394,0.0001567476,0.00001713459],"category_scores_gemma":[0.00006599818,0.0001297453,0.00004395923,0.0002117061,0.0002226895,0.000006444783,0.0002776662,0.0001096977,0.000003099365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001289504,"about_ca_system_score_gemma":0.0001091461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000193305,"about_ca_topic_score_gemma":0.0001891739,"domain_scores_codex":[0.9986488,0.0001647414,0.000220574,0.0004175882,0.000218942,0.0003294129],"domain_scores_gemma":[0.9993432,0.00003994928,0.0000268237,0.0003815162,0.00003030731,0.0001782433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009989276,0.00008731684,0.01292814,0.0007739129,0.00002616421,0.0001713147,0.0004493014,0.00003481484,0.9841348,0.00001348172,0.0002040055,0.001076835],"study_design_scores_gemma":[0.00315714,0.001891872,0.09503078,0.0002068571,0.00005483779,0.00008144822,0.00442025,0.0003318701,0.8728099,0.0001105489,0.02105156,0.0008529489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962811,0.002121245,0.00004458771,0.0004993585,0.00002457992,0.0006196881,0.0002957661,0.00001018166,0.0001034745],"genre_scores_gemma":[0.9979951,0.001169276,0.0000191129,0.0001503727,0.00003912544,0.0002029454,0.00009905206,0.00002115615,0.0003038647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1113249,"threshold_uncertainty_score":0.5290861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02071177880848693,"score_gpt":0.2870032009274365,"score_spread":0.2662914221189496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}