{"id":"W4388712457","doi":"10.32604/or.2023.030401","title":"Biological, pathological, and multifaceted therapeutic functions of exosomes to target cancer","year":2023,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Durham College","funders":"Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education","keywords":"Microvesicles; Exosome; Intracellular; Cell biology; Function (biology); microRNA; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008941427,0.0005407383,0.0004975406,0.001018339,0.0006471577,0.001803546,0.0003313614,0.0009508133,0.001319718],"category_scores_gemma":[0.0007527755,0.0002232635,0.0007689719,0.0005118081,0.0008811619,0.001529403,0.001323904,0.001258875,0.0003514143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006388294,"about_ca_system_score_gemma":0.00090779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003392426,"about_ca_topic_score_gemma":0.0003917831,"domain_scores_codex":[0.9996105,0.0001123577,0.00003558121,0.00006112186,0.0001138528,0.00006658065],"domain_scores_gemma":[0.9997533,0.00006265107,0.00003873243,0.00002484641,0.00007210558,0.00004836948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007696623,0.0003741964,0.009395942,0.005873573,0.0002722479,0.005031873,0.0009600592,0.003204384,0.5451128,0.06494323,0.01544426,0.3486178],"study_design_scores_gemma":[0.0001316888,0.001162462,0.0185899,0.001293216,0.0004683764,0.01762593,0.001132127,0.00567429,0.5510579,0.03881046,0.3638848,0.0001688317],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2596949,0.6036326,0.0736981,0.01985384,0.003261761,0.000484079,0.001148191,0.0007678774,0.03745878],"genre_scores_gemma":[0.7736712,0.1893396,0.0227283,0.002781871,0.0008663503,0.0003410928,0.0005117027,0.00008716081,0.0096729],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001803546,"threshold_uncertainty_score":0.004728734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2954338355755112,"score_gpt":0.527769437303063,"score_spread":0.2323356017275518,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}