{"id":"W4388714065","doi":"10.1016/j.dnarep.2023.103595","title":"The entanglement of DNA damage and pattern recognition receptor signaling","year":2023,"lang":"en","type":"article","venue":"DNA repair","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Terry Fox Research Institute; Princess Margaret Cancer Foundation","keywords":"DNA damage; Biology; DNA repair; Cell biology; DNA; Mitosis; Mutagenesis; Cell cycle; Genome instability; Mitotic catastrophe; Apoptosis; Genetics; Gene; Mutation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004169231,0.0000923668,0.00008192109,0.00002716345,0.00008973732,0.00001320266,0.00009208416,0.00006734047,0.00003002534],"category_scores_gemma":[0.00006772697,0.00007440068,0.00008141132,0.0000842669,0.00004714777,0.000002695741,0.0001290958,0.00004140298,0.00002830466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008482768,"about_ca_system_score_gemma":0.0000164094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009086854,"about_ca_topic_score_gemma":0.00001682913,"domain_scores_codex":[0.9992129,0.00007081439,0.0001872403,0.0002315237,0.0001241361,0.0001734071],"domain_scores_gemma":[0.9995359,0.0000290324,0.0000781289,0.0002648594,0.00004993716,0.00004219018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002415063,0.00001635295,0.0006269763,0.00002196505,0.00004844579,0.00000262894,0.00007271276,0.000001300569,0.9773322,0.00001345315,0.005054623,0.01678513],"study_design_scores_gemma":[0.0002571707,0.0001989533,0.0005560701,0.00002486653,0.00001479885,0.000002526862,0.0004088916,0.000183999,0.9651551,0.0001769325,0.03291234,0.0001083707],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988529,0.0001275489,0.0001033525,0.0002203445,0.0001662362,0.0001778201,0.00003921751,0.0000736572,0.0002388987],"genre_scores_gemma":[0.9980417,0.0002681418,0.0004778311,0.0001749694,0.0001115526,0.00004221949,0.0002546262,0.00002315602,0.0006058365],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02785772,"threshold_uncertainty_score":0.3033971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01477816134997974,"score_gpt":0.2403753358439442,"score_spread":0.2255971744939644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}