{"id":"W4388722018","doi":"10.1182/blood.2023022497","title":"Sphingolipids and HSC fitness: enigma no more","year":2023,"lang":"en","type":"letter","venue":"Blood","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Sphingolipid; Biology; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001732842,0.0005933871,0.001176375,0.0004139427,0.001426496,0.002341487,0.001109676,0.01377755,0.004572653],"category_scores_gemma":[0.006167966,0.0002962123,0.0006556985,0.0003502909,0.002563685,0.00381297,0.0009812845,0.02047762,0.003682102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001903115,"about_ca_system_score_gemma":0.00110565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001055906,"about_ca_topic_score_gemma":0.001517389,"domain_scores_codex":[0.9991233,0.0003301755,0.000108257,0.0001329922,0.0002062996,0.00009902848],"domain_scores_gemma":[0.9971771,0.001644555,0.000173159,0.0001732651,0.000404824,0.0004270308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003962828,0.0001781926,0.002231116,0.000297174,0.00005876808,0.007384189,0.0001756498,0.0001667741,0.001392566,0.01078578,0.8953581,0.08157543],"study_design_scores_gemma":[0.0003446112,0.0002300396,0.002393172,0.0005784988,0.00006527192,0.0133936,0.0007633894,0.001034956,0.0007078397,0.05638273,0.9240186,0.00008738032],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.000899795,0.01456145,0.0001362673,0.9694397,0.01342255,0.000007547889,0.00002384093,0.00002705641,0.001481885],"genre_scores_gemma":[0.01569315,0.0191518,0.0005327239,0.7455429,0.2125386,0.00003212882,0.00003718033,0.00002621145,0.006445315],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01377755,"threshold_uncertainty_score":0.01529706,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00999488938906991,"score_gpt":0.2312167482320542,"score_spread":0.2212218588429843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}