{"id":"W4388727174","doi":"10.1038/s42003-023-05534-2","title":"Systematic investigation of recipient cell genetic requirements reveals important surface receptors for conjugative transfer of IncI2 plasmids","year":2023,"lang":"en","type":"article","venue":"Communications Biology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Université de Sherbrooke; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Plasmid; Pilus; Bacterial conjugation; Biology; Gene; Bacterial adhesin; Horizontal gene transfer; Mutant; Escherichia coli; Genetics; Receptor; Bacterial genetics; Cell; Cell biology; Chromosome; Function (biology); Gene transfer; Bacterial cell structure; Bacteria; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004257159,0.00008986127,0.0002510334,0.00005004893,0.0001039628,0.00000380108,0.0004590509,0.00007702786,0.0001386719],"category_scores_gemma":[0.00008754062,0.00008143289,0.00007352858,0.0003129842,0.0004290564,0.00006049009,0.0001839433,0.00006734922,0.0000459281],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007619621,"about_ca_system_score_gemma":0.00001710498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001851877,"about_ca_topic_score_gemma":0.0001378238,"domain_scores_codex":[0.9987136,0.000254066,0.0006961719,0.0001513555,0.00004873948,0.0001360842],"domain_scores_gemma":[0.9985764,0.0003884047,0.0002668459,0.0006817941,0.00004823445,0.00003830071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009715882,0.00004490976,0.01126002,0.0003320743,0.00002820488,3.369193e-8,0.001042487,0.00006388584,0.9864616,0.0002368443,0.000472559,0.0000477107],"study_design_scores_gemma":[0.001904508,0.001320111,0.1355616,0.002283812,0.0003985292,0.000008593614,0.002840782,0.005868887,0.8393267,0.005626339,0.004136789,0.0007233546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976419,0.0001298077,0.0004512926,0.0002730147,0.0001402005,0.0008388172,0.0001431561,0.00002118112,0.0003605963],"genre_scores_gemma":[0.993318,0.0004839437,0.005598664,0.00003649812,0.000003348546,0.0001070079,0.0001810548,0.00001007047,0.000261463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1471349,"threshold_uncertainty_score":0.3320737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04442103170268265,"score_gpt":0.3005337841139175,"score_spread":0.2561127524112348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}