{"id":"W4388727174","doi":"10.1038/s42003-023-05534-2","title":"Systematic investigation of recipient cell genetic requirements reveals important surface receptors for conjugative transfer of IncI2 plasmids","year":2023,"lang":"en","type":"article","venue":"Communications Biology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Université de Sherbrooke; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Plasmid; Pilus; Bacterial conjugation; Biology; Gene; Bacterial adhesin; Horizontal gene transfer; Mutant; Escherichia coli; Genetics; Receptor; Bacterial genetics; Cell; Cell biology; Chromosome; Function (biology); Gene transfer; Bacterial cell structure; Bacteria; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002655982,0.0005760676,0.0004288144,0.0003715037,0.0001281252,0.000410244,0.0002927835,0.000333806,0.0009069541],"category_scores_gemma":[0.0004936433,0.0001541729,0.0002569513,0.000337977,0.000206512,0.0002901672,0.0003858136,0.0006285797,0.0003279727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002174401,"about_ca_system_score_gemma":0.0001544379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003045401,"about_ca_topic_score_gemma":0.0002485846,"domain_scores_codex":[0.9996805,0.00006138282,0.00002629474,0.00005028876,0.0001173155,0.00006422493],"domain_scores_gemma":[0.9996182,0.0001393494,0.00009511552,0.00006182919,0.00004460475,0.00004096641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001839416,0.00001116014,0.0001727245,0.00000599537,0.000001015516,0.00001488298,0.000004615628,0.00001309042,0.9994887,0.00001663273,0.000002442835,0.0002502851],"study_design_scores_gemma":[0.000002492646,0.0001403108,0.004437408,0.000001737065,0.000009982088,0.0001643622,0.00003815302,0.0005444108,0.9943349,0.00001980867,0.0003030389,0.000003486303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968978,0.0001408379,0.002418664,0.00002755457,0.000004482829,0.00001861382,0.0001296913,0.00003292512,0.0003293352],"genre_scores_gemma":[0.994307,0.0002061083,0.003788221,0.00002109935,0.000003989124,0.00004011536,0.0007388318,0.00004712377,0.0008474642],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009069541,"threshold_uncertainty_score":0.003034055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04442103170268265,"score_gpt":0.3005337841139175,"score_spread":0.2561127524112348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}