{"id":"W4388728147","doi":"10.21203/rs.3.rs-3592492/v1","title":"Dual T Cell Depletion for Graft versus Host Disease Prevention in Peripheral Blood Haploidentical Hematopoietic Cell Transplantation for Adults with Hematological Malignancies","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Hematopoietic cell; Peripheral blood; Immunology; Hematopoietic stem cell transplantation; Graft-versus-host disease; Medicine; Haematopoiesis; Transplantation; Cell; Peripheral; Disease; Biology; Stem cell; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000286631,0.0001905906,0.0002938759,0.0001554879,0.00008955312,0.0002997935,0.0001708659,0.0002105423,0.00225395],"category_scores_gemma":[0.0002484475,0.00006581655,0.0001733796,0.0001106559,0.0001497396,0.0001361287,0.0002640147,0.0005629397,0.0003523802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001025016,"about_ca_system_score_gemma":0.0002577787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001259216,"about_ca_topic_score_gemma":0.0001679457,"domain_scores_codex":[0.9999403,0.00002036378,0.00000312586,0.00001034341,0.00001365938,0.00001223862],"domain_scores_gemma":[0.9999503,0.00001529617,0.000008980774,0.000007366918,0.000004435658,0.0000137516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.02066812,0.001544151,0.0105828,0.0006098801,0.0002144224,0.0006001179,0.0001158857,0.001711212,0.3049704,0.002612733,0.006756122,0.6496142],"study_design_scores_gemma":[0.008839305,0.04083727,0.1344762,0.0006581815,0.001692478,0.007614203,0.0002682011,0.01699534,0.6666756,0.007785126,0.1140946,0.00006350769],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.960508,0.02056715,0.01205356,0.0009343894,0.0002768647,0.0001411673,0.0003419592,0.0001558077,0.005021131],"genre_scores_gemma":[0.9859173,0.003676066,0.007115938,0.0002367403,0.0001395809,0.0001253893,0.0003855235,0.000027679,0.002375799],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00225395,"threshold_uncertainty_score":0.007540226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06973032768981986,"score_gpt":0.3697413414777562,"score_spread":0.3000110137879364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}